Inducible expression of bcl-2 antisense RNA promotes apoptosis of human gastric cancer cell line

Jie Zhang; Wei Dan Peng; Hong Xiang Hui; Ming Jin; Duo Ning Wang; Cheng Ji Wang; Huan Wen Qian

Inducible expression of bcl-2 antisense RNA promotes apoptosis of human gastric cancer cell line

Jie Zhang^*, Wei Dan Peng, Hong Xiang Hui, Ming Jin, Duo Ning Wang, Cheng Ji Wang, Huan Wen Qian

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A lot of molecular biological techniques was used to observe the effect of bcl-2 antisence RNA on human gastric cancer cell line SGC7901 and to detect the inducibility and promotion of MT-II promoter. The results showed that MT-II promoter could be activated by the induction with 160 μmol/L Zn²⁺ and the expression of Bcl-2 plays an important role in apoptosis of SGC7901 cells.

Original language	English
Pages (from-to)	282-283
Number of pages	2
Journal	Acta Biochimica et Biophysica Sinica
Volume	31
Issue number	3
Publication status	Published - 1999
Externally published	Yes

Keywords

Antisense
Apoptosis
Bcl-2
Gene therapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Inducible expression of bcl-2 antisense RNA promotes apoptosis of human gastric cancer cell line",

abstract = "A lot of molecular biological techniques was used to observe the effect of bcl-2 antisence RNA on human gastric cancer cell line SGC7901 and to detect the inducibility and promotion of MT-II promoter. The results showed that MT-II promoter could be activated by the induction with 160 μmol/L Zn2+ and the expression of Bcl-2 plays an important role in apoptosis of SGC7901 cells.",

keywords = "Antisense, Apoptosis, Bcl-2, Gene therapy",

author = "Jie Zhang and Peng, {Wei Dan} and Hui, {Hong Xiang} and Ming Jin and Wang, {Duo Ning} and Wang, {Cheng Ji} and Qian, {Huan Wen}",

year = "1999",

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volume = "31",

pages = "282--283",

journal = "Acta Biochimica et Biophysica Sinica",

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TY - JOUR

T1 - Inducible expression of bcl-2 antisense RNA promotes apoptosis of human gastric cancer cell line

AU - Zhang, Jie

AU - Peng, Wei Dan

AU - Hui, Hong Xiang

AU - Jin, Ming

AU - Wang, Duo Ning

AU - Wang, Cheng Ji

AU - Qian, Huan Wen

PY - 1999

Y1 - 1999

N2 - A lot of molecular biological techniques was used to observe the effect of bcl-2 antisence RNA on human gastric cancer cell line SGC7901 and to detect the inducibility and promotion of MT-II promoter. The results showed that MT-II promoter could be activated by the induction with 160 μmol/L Zn2+ and the expression of Bcl-2 plays an important role in apoptosis of SGC7901 cells.

AB - A lot of molecular biological techniques was used to observe the effect of bcl-2 antisence RNA on human gastric cancer cell line SGC7901 and to detect the inducibility and promotion of MT-II promoter. The results showed that MT-II promoter could be activated by the induction with 160 μmol/L Zn2+ and the expression of Bcl-2 plays an important role in apoptosis of SGC7901 cells.

KW - Antisense

KW - Apoptosis

KW - Bcl-2

KW - Gene therapy

UR - http://www.scopus.com/inward/record.url?scp=20444417492&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:20444417492

SN - 0582-9879

VL - 31

SP - 282

EP - 283

JO - Acta Biochimica et Biophysica Sinica

JF - Acta Biochimica et Biophysica Sinica

IS - 3

ER -

Inducible expression of bcl-2 antisense RNA promotes apoptosis of human gastric cancer cell line

Abstract

Keywords

UN SDGs

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