Implication of oxidative stress-induced oncogenic signaling pathways as a treatment strategy for neurodegeneration and cancer

Gjumrakch Aliev; Gregory Burzynski; Ghulam Md Ashraf; Nasimudeen R. Jabir; Ramon Cacabelos; Valery V. Benberin; Stanislaw R. Burzynski

doi:10.1007/978-3-642-30018-9_206

Implication of oxidative stress-induced oncogenic signaling pathways as a treatment strategy for neurodegeneration and cancer

Gjumrakch Aliev^*, Gregory Burzynski, Ghulam Md Ashraf, Nasimudeen R. Jabir, Ramon Cacabelos, Valery V. Benberin, Stanislaw R. Burzynski

^*Corresponding author for this work

Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review

16 Citations (Scopus)

Abstract

Recent evidence has associated the aberrant, proximal reexpression of various cell cycle control elements with neuronal cell vulnerability in Alzheimer and Parkinson's diseases, as a common chronic neurodegeneration. This phenomenon associated with oncogenic transduction pathways activation has attracted the interest of scientists all over the world for a few years now. The purpose of this chapter is to outline areas of research related to oxidative stress induced oncogenic factors or medicines in the context of potential applications for future treatment of the above mentioned chronic and, largely, incurable diseases.

Original language	English
Title of host publication	Systems Biology of Free Radicals and Antioxidants
Publisher	Springer-Verlag Berlin Heidelberg
Pages	2325-2347
Number of pages	23
ISBN (Electronic)	9783642300189
ISBN (Print)	3642300170, 9783642300172
DOIs	https://doi.org/10.1007/978-3-642-30018-9_206
Publication status	Published - 1 May 2012
Externally published	Yes

Keywords

Alzheimer's disease
Cancer
Cell Cycle
Mitochondria
Oncogenes
Oxidative stress

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/978-3-642-30018-9_206

Cite this

Aliev, G., Burzynski, G., Ashraf, G. M., Jabir, N. R., Cacabelos, R., Benberin, V. V., & Burzynski, S. R. (2012). Implication of oxidative stress-induced oncogenic signaling pathways as a treatment strategy for neurodegeneration and cancer. In Systems Biology of Free Radicals and Antioxidants (pp. 2325-2347). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-30018-9_206

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abstract = "Recent evidence has associated the aberrant, proximal reexpression of various cell cycle control elements with neuronal cell vulnerability in Alzheimer and Parkinson's diseases, as a common chronic neurodegeneration. This phenomenon associated with oncogenic transduction pathways activation has attracted the interest of scientists all over the world for a few years now. The purpose of this chapter is to outline areas of research related to oxidative stress induced oncogenic factors or medicines in the context of potential applications for future treatment of the above mentioned chronic and, largely, incurable diseases.",

keywords = "Alzheimer's disease, Cancer, Cell Cycle, Mitochondria, Oncogenes, Oxidative stress",

author = "Gjumrakch Aliev and Gregory Burzynski and Ashraf, {Ghulam Md} and Jabir, {Nasimudeen R.} and Ramon Cacabelos and Benberin, {Valery V.} and Burzynski, {Stanislaw R.}",

note = "Publisher Copyright: {\textcopyright} Springer-Verlag Berlin Heidelberg 2014. All rights are reserved.",

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doi = "10.1007/978-3-642-30018-9_206",

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Aliev, G, Burzynski, G, Ashraf, GM, Jabir, NR, Cacabelos, R, Benberin, VV & Burzynski, SR 2012, Implication of oxidative stress-induced oncogenic signaling pathways as a treatment strategy for neurodegeneration and cancer. in Systems Biology of Free Radicals and Antioxidants. Springer-Verlag Berlin Heidelberg, pp. 2325-2347. https://doi.org/10.1007/978-3-642-30018-9_206

Implication of oxidative stress-induced oncogenic signaling pathways as a treatment strategy for neurodegeneration and cancer. / Aliev, Gjumrakch; Burzynski, Gregory; Ashraf, Ghulam Md et al.
Systems Biology of Free Radicals and Antioxidants. Springer-Verlag Berlin Heidelberg, 2012. p. 2325-2347.

Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Implication of oxidative stress-induced oncogenic signaling pathways as a treatment strategy for neurodegeneration and cancer

AU - Aliev, Gjumrakch

AU - Burzynski, Gregory

AU - Ashraf, Ghulam Md

AU - Jabir, Nasimudeen R.

AU - Cacabelos, Ramon

AU - Benberin, Valery V.

AU - Burzynski, Stanislaw R.

N1 - Publisher Copyright: © Springer-Verlag Berlin Heidelberg 2014. All rights are reserved.

PY - 2012/5/1

Y1 - 2012/5/1

N2 - Recent evidence has associated the aberrant, proximal reexpression of various cell cycle control elements with neuronal cell vulnerability in Alzheimer and Parkinson's diseases, as a common chronic neurodegeneration. This phenomenon associated with oncogenic transduction pathways activation has attracted the interest of scientists all over the world for a few years now. The purpose of this chapter is to outline areas of research related to oxidative stress induced oncogenic factors or medicines in the context of potential applications for future treatment of the above mentioned chronic and, largely, incurable diseases.

AB - Recent evidence has associated the aberrant, proximal reexpression of various cell cycle control elements with neuronal cell vulnerability in Alzheimer and Parkinson's diseases, as a common chronic neurodegeneration. This phenomenon associated with oncogenic transduction pathways activation has attracted the interest of scientists all over the world for a few years now. The purpose of this chapter is to outline areas of research related to oxidative stress induced oncogenic factors or medicines in the context of potential applications for future treatment of the above mentioned chronic and, largely, incurable diseases.

KW - Alzheimer's disease

KW - Cancer

KW - Cell Cycle

KW - Mitochondria

KW - Oncogenes

KW - Oxidative stress

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U2 - 10.1007/978-3-642-30018-9_206

DO - 10.1007/978-3-642-30018-9_206

M3 - Chapter

AN - SCOPUS:84929138425

SN - 3642300170

SN - 9783642300172

SP - 2325

EP - 2347

BT - Systems Biology of Free Radicals and Antioxidants

PB - Springer-Verlag Berlin Heidelberg

ER -

Implication of oxidative stress-induced oncogenic signaling pathways as a treatment strategy for neurodegeneration and cancer

Abstract

Keywords

UN SDGs

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