Impact of Common Natural Compound in the Treatment of Alzheimer’s Disease

Vishav Prabhjot Kaur; Sachchida Nand Rai; Tania Bajaj; Hemraj Heer; Vishal Puri; Vivek K. Chaturvedi; Arti Singh; Ghulam Md Ashraf; M. P. Singh; Charan Singh

doi:10.1007/978-981-16-4558-7_4

Impact of Common Natural Compound in the Treatment of Alzheimer’s Disease

Vishav Prabhjot Kaur, Sachchida Nand Rai, Tania Bajaj, Hemraj Heer, Vishal Puri, Vivek K. Chaturvedi, Arti Singh, Ghulam Md Ashraf, M. P. Singh, Charan Singh^*

^*Corresponding author for this work

Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review

Abstract

Alzheimer’s disease (AD) is considered one of the most complex neurodegenerative disorders. Amyloid and tau pathology, along with neurofibrillary tangles, are most commonly seen in this disease. Various compounds show promising responses in treating this disease, but they also cause severe side effects. To minimize these side effects, researchers explored several natural products for the treatment of this disease. Natural products cause very minimal side effects as compared to isolated chemical compounds. The minimal side effect might be due to the complex synergistic effects of various bioactive components present in these natural products. Several natural products like green tea, epigallocatechin gallate, baicalein, berberine, and quercetin show a robust response in the treatment of AD. Some natural compounds like Ginkgo biloba extract and Huperzine A passed the clinical trial on PD. This chapter has explored the potential of some of the most common natural products to treat AD in a sequence-wide manner.

Original language	English
Title of host publication	Autism Spectrum Disorder and Alzheimers Disease
Subtitle of host publication	Advances in Research
Publisher	Springer Nature
Pages	63-82
Number of pages	20
ISBN (Electronic)	9789811645587
ISBN (Print)	9789811645570
DOIs	https://doi.org/10.1007/978-981-16-4558-7_4
Publication status	Published - 1 Jan 2022
Externally published	Yes

Keywords

Alzheimer’s disease
Baicalein
Clinical trials
Epigallocatechin
Green tea

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10.1007/978-981-16-4558-7_4

Cite this

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abstract = "Alzheimer{\textquoteright}s disease (AD) is considered one of the most complex neurodegenerative disorders. Amyloid and tau pathology, along with neurofibrillary tangles, are most commonly seen in this disease. Various compounds show promising responses in treating this disease, but they also cause severe side effects. To minimize these side effects, researchers explored several natural products for the treatment of this disease. Natural products cause very minimal side effects as compared to isolated chemical compounds. The minimal side effect might be due to the complex synergistic effects of various bioactive components present in these natural products. Several natural products like green tea, epigallocatechin gallate, baicalein, berberine, and quercetin show a robust response in the treatment of AD. Some natural compounds like Ginkgo biloba extract and Huperzine A passed the clinical trial on PD. This chapter has explored the potential of some of the most common natural products to treat AD in a sequence-wide manner.",

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AU - Puri, Vishal

AU - Chaturvedi, Vivek K.

AU - Singh, Arti

AU - Ashraf, Ghulam Md

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Impact of Common Natural Compound in the Treatment of Alzheimer’s Disease

Abstract

Keywords

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