GCSBA-Net: Gabor-Based and Cascade Squeeze Bi-Attention Network for Gland Segmentation

Zhijie Wen, Ru Feng, Jingxin Liu, Ying Li, Shihui Ying*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

Colorectal cancer is the second and the third most common cancer in women and men, respectively. Pathological diagnosis is the 'gold standard' for tumor diagnosis. Accurate segmentation of glands from tissue images is a crucial step in assisting pathologists in their diagnosis. The typical methods for gland segmentation form a dense image representation, ignoring its texture and multi-scale attention information. Therefore, we utilize a Gabor-based module to extract texture information at different scales and directions in histopathology images. This paper also designs a Cascade Squeeze Bi-Attention (CSBA) module. Specifically, we add Atrous Cascade Spatial Pyramid (ACSP), Squeeze Position Attention (SPA) module and Squeeze Channel Attention module (SCA) to model semantic correlation and maintain the multi-level aggregation on the spatial pyramid with different dilations. Besides, to solve the imbalance of data distribution and boundary blur, we propose a hybrid loss function to response the object boudary better. The experimental results show that the proposed method achieves state-of-The-Art performance on the GlaS challenge dataset and CRAG colorectal adenocarcinoma dataset, respectively.

Original languageEnglish
Article number9164951
Pages (from-to)1185-1196
Number of pages12
JournalIEEE Journal of Biomedical and Health Informatics
Volume25
Issue number4
DOIs
Publication statusPublished - Apr 2021
Externally publishedYes

Keywords

  • Gabor-based encoder module
  • cascade squeeze bi-Attention
  • gland segmentation
  • hybrid loss function

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