Abstract
Synthesis of modified EDTA and DTPA ligands and determination of their binding affinities for the uranyl cation are described. Thanks to a screening method, based on a chromophoric complex displacement procedure, chelating properties were studied in aqueous media under various pH conditions for evaluation of their in vivo uranyl-removal efficacy. Each ligand showed a more or less pronounced affinity for uranium. Specific ligands based on EDTA or DTPA analogues containing sulfocatecholamide (CAMS) were found to exhibit a significant affinity towards uranyl ion in acidic, neutral or basic conditions.
Original language | English |
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Pages (from-to) | 1163-1170 |
Number of pages | 8 |
Journal | Tetrahedron |
Volume | 68 |
Issue number | 4 |
DOIs | |
Publication status | Published - 28 Jan 2012 |
Externally published | Yes |