Detection of dendritic spines using wavelet packet entropy and fuzzy support vector machine

Shuihua Wang, Yang Li, Ying Shao, Carlo Cattani, Yudong Zhang, Sidan Du*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

62 Citations (Scopus)

Abstract

The morphology of dendritic spines is highly correlated with the neuron function. Therefore, it is of positive influence for the research of the dendritic spines. However, it is tried to manually label the spine types for statistical analysis. In this work, we proposed an approach based on the combination of wavelet contour analysis for the backbone detection, wavelet packet entropy, and fuzzy support vector machine for the spine classification. The experiments show that this approach is promising. The average detection accuracy of “MushRoom” achieves 97.3%, “Stubby” achieves 94.6%, and “Thin” achieves 97.2%.

Original languageEnglish
Pages (from-to)116-121
Number of pages6
JournalCNS and Neurological Disorders - Drug Targets
Volume16
Issue number2
DOIs
Publication statusPublished - 2017
Externally publishedYes

Keywords

  • Dendritic spines
  • Discrete wavelet transform
  • Fuzzy support vector machine
  • Wavelet packet entropy

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