Designing Highly Sensitive Microwave Antenna Sensor with Novel Model for Noninvasive Glucose Measurements

Abhishek Kandwal, Louis W.Y. Liu, Jingzhen Li, Yuhang Liu, Huajie Tang, Ziheng Ju, Tobore Igbe, Rohit Jasrotia, Zedong Nie*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

—The concentration induced permittivity change involves a dispersion which occurs at the resonant frequency and is often not predictable by simulation using the traditional Cole-Cole model. To overcome this problem, a new Lorentz’s model is proposed as a substitute for the Cole-Cole model. Under this new model, the glucose concentration is expected to be measured at the contact interface in the form of a resonant frequency shift. With the help of the model, a contact-based meander-line antenna sensor (CMS) is realized with a high sensitivity of 1.3158 dB/(mmol/L) in terms of d|S11 |/dC, or of 17 ∼ 18 MHz/(mmol/L) in terms of dω/dC. The model has been experimentally validated with in-vitro measurements and for proof-of-concept with in-vivo clinical investigations in the microwave frequency. Consistent with the predictions of model, a linear correlation is observed not only between the resonant frequency shift and the glucose concentration, but also between the S-parameters magnitude and glucose concentration.

Original languageEnglish
Pages (from-to)129-141
Number of pages13
JournalProgress in Electromagnetics Research
Volume176
DOIs
Publication statusPublished - 2023
Externally publishedYes

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