Design of an Optical Probe to Monitor Vaginal Hemodynamics during Sexual Arousal

Hyeryun Jeong, Myeongsu Seong, Hyun Suk Lee, Kwangsung Park, Sucbei Moon, Jae Gwan Kim

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


An optical probe was developed to measure the change of oxy-hemoglobin (OHb), deoxy- hemoglobin (RHb), and total hemoglobin (THb) along with temperature from the vaginal wall of female rats. Apomorphine (APO, 80 μg/kg) was administered to elicit sexual arousal in female Sprague Dawley rats (SD, 180-200 g). The behavior changes caused by APO administration were checked before monitoring vaginal responses. The changes of oxy-, deoxy-, and total hemoglobin concentration and the temperature from the vaginal wall were monitored before, during, and after APO administration. Animals were under anesthesia during the measurement. After APO administration, the concentration of OHb (55 ± 29 μM/DPF), RHb (33 ± 25 μM/DPF), and THb (83 ± 59 μM/DPF) in the vaginal wall increased in a few min, while saline administration did not cause any significant change. In case of the vaginal temperature change, APO decreased the temperature slightly in the vaginal wall while saline administration did not show any temperature change in the vaginal wall. As the outcomes demonstrated, the developed probe can detect hemodynamic and temperature variation in the vaginal wall. The hemodynamic information acquired by the probe can be utilized to establish an objective and accurate standard of female sexual disorders.

Original languageEnglish
JournalSensors (Basel, Switzerland)
Issue number9
Publication statusPublished - 8 May 2019
Externally publishedYes


  • apomorphine
  • female sexual dysfunction
  • hemodynamics
  • sexual arousal
  • temperature
  • vaginal wall


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