Breast microscopic cancer segmentation and classification using unique 4-qubit-quantum model

Javaria Amin, Muhammad Sharif, Steven Lawrence Fernandes, Shui Hua Wang, Tanzila Saba*, Amjad Rehman Khan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


The visual inspection of histopathological samples is the benchmark for detecting breast cancer, but a strenuous and complicated process takes a long time of the pathologist practice. Deep learning models have shown excellent outcomes in clinical diagnosis and image processing and advances in various fields, including drug development, frequency simulation, and optimization techniques. However, the resemblance of histopathologic images of breast cancer and the inclusion of stable and infected tissues in different areas make detecting and classifying tumors on entire slide images more difficult. In breast cancer, a correct diagnosis is needed for complete care in a limited amount of time. An effective detection can relieve the pathologist's workload and mitigate diagnostic subjectivity. Therefore, this research work investigates improved the pre-trained xception and deeplabv3+ design semantic model. The model has been trained on input images with ground masks on the tuned parameters that significantly improve the segmentation of ultrasound breast images into respective classes, that is, benign/malignant. The segmentation model delivered an accuracy of greater than 99% to prove the model's effectiveness. The segmented images and histopathological breast images are transferred to the 4-qubit-quantum circuit with six-layered architecture to detect breast malignancy. The proposed framework achieved remarkable performance as contrasted to currently published methodologies. Highlights: This research proposed hybrid semantic model using pre-trained xception and deeplabv3 for breast microscopic cancer classification in to benign and malignant classes at accuracy of 95% accuracy, 99% accuracy for detection of breast malignancy.

Original languageEnglish
Pages (from-to)1926-1936
Number of pages11
JournalMicroscopy Research and Technique
Issue number5
Publication statusPublished - May 2022
Externally publishedYes


  • 4-qubit-quantum circuit
  • ReLU
  • breast cancer
  • deeplabv3
  • health care
  • public health
  • xception


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