TY - JOUR
T1 - Application of efficient nanoparticles for early diagnosis and treatment of cancer
AU - Alexiou, Athanasios
AU - Vairaktarakis, Charalampos
AU - Tsiamis, Vasilis
AU - Ashraf, Ghulam Md
N1 - Publisher Copyright:
© 2015 Bentham Science Publishers.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Cancer is considered as a prevalent cause of human deaths and undoubtedly, is the most complex disease with multiple cellular physiological systems involved. During the last decade, the application of nanotechnological products for cancer treatment has received considerable attention. These sophisticated tools and materials treat cancer though the early diagnosis, the prediction, the prevention and the personalized therapy. This technology enabled the development of nanoscale particles that can be conjugated with one or multiple functional molecules simultaneously. Nanoparticles have the capability to be delivered directly through blood vessels to the tumor site and interact with targeted tumor-specific proteins located inside or on the surface of cancer cells, since their size is a hundred to thousand times smaller than cancer cells. In this review, comprehensive outline of all the latest scientific and technological applications such as quantum dots and gold nanoparticles alongside with their applications in cancer diagnosis and treatment have been presented.
AB - Cancer is considered as a prevalent cause of human deaths and undoubtedly, is the most complex disease with multiple cellular physiological systems involved. During the last decade, the application of nanotechnological products for cancer treatment has received considerable attention. These sophisticated tools and materials treat cancer though the early diagnosis, the prediction, the prevention and the personalized therapy. This technology enabled the development of nanoscale particles that can be conjugated with one or multiple functional molecules simultaneously. Nanoparticles have the capability to be delivered directly through blood vessels to the tumor site and interact with targeted tumor-specific proteins located inside or on the surface of cancer cells, since their size is a hundred to thousand times smaller than cancer cells. In this review, comprehensive outline of all the latest scientific and technological applications such as quantum dots and gold nanoparticles alongside with their applications in cancer diagnosis and treatment have been presented.
KW - Cancer diagnosis and treatment
KW - Drug delivery
KW - Gold nanoparticles
KW - Nanomedicine
KW - Quantum dots
UR - http://www.scopus.com/inward/record.url?scp=84947903123&partnerID=8YFLogxK
U2 - 10.2174/1389200216666150602145310
DO - 10.2174/1389200216666150602145310
M3 - Article
C2 - 26560321
AN - SCOPUS:84947903123
SN - 1389-2002
VL - 16
SP - 662
EP - 675
JO - Current Drug Metabolism
JF - Current Drug Metabolism
IS - 8
ER -
