Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent

Qian Zhang; Jaya P. Shrestha; Cheng Wei Tom Chang

doi:10.1016/j.tetlet.2014.01.129

Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent

Qian Zhang
, Jaya P. Shrestha
, Cheng Wei Tom Chang^*

^*Corresponding author for this work

Utah State University

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2, 3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.

Original language	English
Pages (from-to)	1839-1842
Number of pages	4
Journal	Tetrahedron Letters
Volume	55
Issue number	10
DOIs	https://doi.org/10.1016/j.tetlet.2014.01.129
Publication status	Published - 5 Mar 2014
Externally published	Yes

Keywords

Bioactive
Green chemistry
Indanedione
Naphthoquinone
Water as solvent

Access to Document

10.1016/j.tetlet.2014.01.129

Cite this

@article{6f58dc11ecae48c1abe4a407b82c7e58,

title = "Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent",

abstract = "Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2, 3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.",

keywords = "Bioactive, Green chemistry, Indanedione, Naphthoquinone, Water as solvent",

author = "Qian Zhang and Shrestha, \{Jaya P.\} and Chang, \{Cheng Wei Tom\}",

note = "Funding Information: We acknowledge the support from the Department of Chemistry and Biochemistry, Utah State University. ",

year = "2014",

month = mar,

day = "5",

doi = "10.1016/j.tetlet.2014.01.129",

language = "English",

volume = "55",

pages = "1839--1842",

journal = "Tetrahedron Letters",

issn = "0040-4039",

number = "10",

}

TY - JOUR

T1 - Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent

AU - Zhang, Qian

AU - Shrestha, Jaya P.

AU - Chang, Cheng Wei Tom

N1 - Funding Information: We acknowledge the support from the Department of Chemistry and Biochemistry, Utah State University.

PY - 2014/3/5

Y1 - 2014/3/5

N2 - Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2, 3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.

AB - Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2, 3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.

KW - Bioactive

KW - Green chemistry

KW - Indanedione

KW - Naphthoquinone

KW - Water as solvent

UR - https://www.scopus.com/pages/publications/84896710012

U2 - 10.1016/j.tetlet.2014.01.129

DO - 10.1016/j.tetlet.2014.01.129

M3 - Article

AN - SCOPUS:84896710012

SN - 0040-4039

VL - 55

SP - 1839

EP - 1842

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 10

ER -

Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this