Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment

Chang Yang; Lun Ma; Xiaoju Zou; Guangya Xiang; Wei Chen

doi:10.1007/s12645-013-0039-2

Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment

Chang Yang
, Lun Ma
, Xiaoju Zou
, Guangya Xiang^*
, Wei Chen

^*Corresponding author for this work

University of Texas at Arlington
Huazhong University of Science and Technology

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are the low cost, simple, and easy preparation and small size for targeting. However, the CuS nanoparticle PTT efficacy needs to be improved for practical applications. In this study, the CuS nano-PTT efficiency is enhanced via the local field enhancement from Ag nanoparticle surface plasmon coupling. The results show that absorbance of CuS nanoparticles in Ag/CuS nanocomposites is enhanced about four times by Ag nanoparticle surface plasmon coupling. Consequently, the PTT efficacy is enhanced and a power of 0.6 W/cm² with a 980-nm laser is sufficient for Ag/CuS nano-PTT activation for cancer treatment in vitro observations.

Original language	English
Pages (from-to)	81-89
Number of pages	9
Journal	Cancer Nanotechnology
Volume	4
Issue number	4-5
DOIs	https://doi.org/10.1007/s12645-013-0039-2
Publication status	Published - Aug 2013
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Ag/CuS nanocomposites
Cancer treatment
Local field enhancement
Photothermal therapy
Surface plasmon resonance

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10.1007/s12645-013-0039-2

Cite this

@article{bc9eb31f4825451dac7bc9463ccc04f1,

title = "Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment",

abstract = "Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are the low cost, simple, and easy preparation and small size for targeting. However, the CuS nanoparticle PTT efficacy needs to be improved for practical applications. In this study, the CuS nano-PTT efficiency is enhanced via the local field enhancement from Ag nanoparticle surface plasmon coupling. The results show that absorbance of CuS nanoparticles in Ag/CuS nanocomposites is enhanced about four times by Ag nanoparticle surface plasmon coupling. Consequently, the PTT efficacy is enhanced and a power of 0.6 W/cm2 with a 980-nm laser is sufficient for Ag/CuS nano-PTT activation for cancer treatment in vitro observations.",

keywords = "Ag/CuS nanocomposites, Cancer treatment, Local field enhancement, Photothermal therapy, Surface plasmon resonance",

author = "Chang Yang and Lun Ma and Xiaoju Zou and Guangya Xiang and Wei Chen",

year = "2013",

month = aug,

doi = "10.1007/s12645-013-0039-2",

language = "English",

volume = "4",

pages = "81--89",

journal = "Cancer Nanotechnology",

issn = "1868-6958",

number = "4-5",

}

TY - JOUR

T1 - Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment

AU - Yang, Chang

AU - Ma, Lun

AU - Zou, Xiaoju

AU - Xiang, Guangya

AU - Chen, Wei

PY - 2013/8

Y1 - 2013/8

N2 - Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are the low cost, simple, and easy preparation and small size for targeting. However, the CuS nanoparticle PTT efficacy needs to be improved for practical applications. In this study, the CuS nano-PTT efficiency is enhanced via the local field enhancement from Ag nanoparticle surface plasmon coupling. The results show that absorbance of CuS nanoparticles in Ag/CuS nanocomposites is enhanced about four times by Ag nanoparticle surface plasmon coupling. Consequently, the PTT efficacy is enhanced and a power of 0.6 W/cm2 with a 980-nm laser is sufficient for Ag/CuS nano-PTT activation for cancer treatment in vitro observations.

AB - Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are the low cost, simple, and easy preparation and small size for targeting. However, the CuS nanoparticle PTT efficacy needs to be improved for practical applications. In this study, the CuS nano-PTT efficiency is enhanced via the local field enhancement from Ag nanoparticle surface plasmon coupling. The results show that absorbance of CuS nanoparticles in Ag/CuS nanocomposites is enhanced about four times by Ag nanoparticle surface plasmon coupling. Consequently, the PTT efficacy is enhanced and a power of 0.6 W/cm2 with a 980-nm laser is sufficient for Ag/CuS nano-PTT activation for cancer treatment in vitro observations.

KW - Ag/CuS nanocomposites

KW - Cancer treatment

KW - Local field enhancement

KW - Photothermal therapy

KW - Surface plasmon resonance

UR - https://www.scopus.com/pages/publications/84880796128

U2 - 10.1007/s12645-013-0039-2

DO - 10.1007/s12645-013-0039-2

M3 - Article

AN - SCOPUS:84880796128

SN - 1868-6958

VL - 4

SP - 81

EP - 89

JO - Cancer Nanotechnology

JF - Cancer Nanotechnology

IS - 4-5

ER -

Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment

Abstract

UN SDGs

Keywords

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