Strengthen alzheimer’s awareness through biomusic

Panagiota Simou; Pavlos Vakalos; Athanasios Alexiou; Stylianos Chatzichronis; Mahmoud A. Ali; Ioannis Haranas; Ioannis Gkigkitzis; Abdul Hafeez; Asma Perveen; Ghulam Md Ashraf

doi:10.1007/978-981-13-9636-6_6

Strengthen alzheimer’s awareness through biomusic

Panagiota Simou
, Pavlos Vakalos
, Athanasios Alexiou^*
, Stylianos Chatzichronis
, Mahmoud A. Ali
, Ioannis Haranas
, Ioannis Gkigkitzis
, Abdul Hafeez
, Asma Perveen
, Ghulam Md Ashraf

^*Corresponding author for this work

Novel Global Community Educational Foundation
Independent Musician-Researcher
AFNP Med
National and Kapodistrian University of Athens
Cairo University
Wilfrid Laurier University
NOVA
Glocal University
King Fahd Medical Research Center (GMA)
King Abdulaziz University
Department of Medical Laboratory Technology

Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

A large number of neurodegenerative diseases, the age-related dementia, and the human frailty are caused, among others, from non-folding proteins and the aggregation of them leading to neuronal death. In the case of Alzheimer’s disease, a significant number of proteins like amyloid beta and tau seem to form unordered and problematic structures, leading through unknown mechanisms to pathological conditions and implications. Additionally, few studies have already shown the possibility of composing music sculptures retrieved from biological data, either for music audience or for cases of art therapy. In this study, we use a novel algorithm in order to present complex sound sculptures based on a hypothetical computerized interaction of amyloid beta and tau. The designed algorithm is completely adjustable, regarding several sound parameters, recognizing and emphasizing common patterns between the tested proteins for the generation of acoustic stimulus to the audience, and revealing Alzheimer’s complexity and tragedy.

Original language	English
Title of host publication	Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease
Subtitle of host publication	Non-Pharmacological Therapies for Alzheimer's Disease
Publisher	Springer Singapore
Pages	117-128
Number of pages	12
ISBN (Electronic)	9789811396366
ISBN (Print)	9789811396359
DOIs	https://doi.org/10.1007/978-981-13-9636-6_6
Publication status	Published - 1 Jan 2019
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Alzheimer’s disease
Amino acids
Amyloid beta protein
Art therapy
Music neuroscience
Musical instrument digital interface
Neuroscience education
Tau protein

Access to Document

10.1007/978-981-13-9636-6_6

Cite this

Simou, P., Vakalos, P., Alexiou, A., Chatzichronis, S., Ali, M. A., Haranas, I., Gkigkitzis, I., Hafeez, A., Perveen, A., & Ashraf, G. M. (2019). Strengthen alzheimer’s awareness through biomusic. In Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease: Non-Pharmacological Therapies for Alzheimer's Disease (pp. 117-128). Springer Singapore. https://doi.org/10.1007/978-981-13-9636-6_6

@inbook{b1a974dc626041f2806f679ca2e3da6a,

title = "Strengthen alzheimer{\textquoteright}s awareness through biomusic",

abstract = "A large number of neurodegenerative diseases, the age-related dementia, and the human frailty are caused, among others, from non-folding proteins and the aggregation of them leading to neuronal death. In the case of Alzheimer{\textquoteright}s disease, a significant number of proteins like amyloid beta and tau seem to form unordered and problematic structures, leading through unknown mechanisms to pathological conditions and implications. Additionally, few studies have already shown the possibility of composing music sculptures retrieved from biological data, either for music audience or for cases of art therapy. In this study, we use a novel algorithm in order to present complex sound sculptures based on a hypothetical computerized interaction of amyloid beta and tau. The designed algorithm is completely adjustable, regarding several sound parameters, recognizing and emphasizing common patterns between the tested proteins for the generation of acoustic stimulus to the audience, and revealing Alzheimer{\textquoteright}s complexity and tragedy.",

keywords = "Alzheimer{\textquoteright}s disease, Amino acids, Amyloid beta protein, Art therapy, Music neuroscience, Musical instrument digital interface, Neuroscience education, Tau protein",

author = "Panagiota Simou and Pavlos Vakalos and Athanasios Alexiou and Stylianos Chatzichronis and Ali, \{Mahmoud A.\} and Ioannis Haranas and Ioannis Gkigkitzis and Abdul Hafeez and Asma Perveen and Ashraf, \{Ghulam Md\}",

note = "Publisher Copyright: {\textcopyright} Springer Nature Singapore Pte Ltd. 2019.",

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doi = "10.1007/978-981-13-9636-6\_6",

language = "English",

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booktitle = "Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease",

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}

Simou, P, Vakalos, P, Alexiou, A, Chatzichronis, S, Ali, MA, Haranas, I, Gkigkitzis, I, Hafeez, A, Perveen, A & Ashraf, GM 2019, Strengthen alzheimer’s awareness through biomusic. in Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease: Non-Pharmacological Therapies for Alzheimer's Disease. Springer Singapore, pp. 117-128. https://doi.org/10.1007/978-981-13-9636-6_6

Strengthen alzheimer’s awareness through biomusic. / Simou, Panagiota; Vakalos, Pavlos; Alexiou, Athanasios et al.
Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease: Non-Pharmacological Therapies for Alzheimer's Disease. Springer Singapore, 2019. p. 117-128.

Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review

TY - CHAP

T1 - Strengthen alzheimer’s awareness through biomusic

AU - Simou, Panagiota

AU - Vakalos, Pavlos

AU - Alexiou, Athanasios

AU - Chatzichronis, Stylianos

AU - Ali, Mahmoud A.

AU - Haranas, Ioannis

AU - Gkigkitzis, Ioannis

AU - Hafeez, Abdul

AU - Perveen, Asma

AU - Ashraf, Ghulam Md

PY - 2019/1/1

Y1 - 2019/1/1

N2 - A large number of neurodegenerative diseases, the age-related dementia, and the human frailty are caused, among others, from non-folding proteins and the aggregation of them leading to neuronal death. In the case of Alzheimer’s disease, a significant number of proteins like amyloid beta and tau seem to form unordered and problematic structures, leading through unknown mechanisms to pathological conditions and implications. Additionally, few studies have already shown the possibility of composing music sculptures retrieved from biological data, either for music audience or for cases of art therapy. In this study, we use a novel algorithm in order to present complex sound sculptures based on a hypothetical computerized interaction of amyloid beta and tau. The designed algorithm is completely adjustable, regarding several sound parameters, recognizing and emphasizing common patterns between the tested proteins for the generation of acoustic stimulus to the audience, and revealing Alzheimer’s complexity and tragedy.

AB - A large number of neurodegenerative diseases, the age-related dementia, and the human frailty are caused, among others, from non-folding proteins and the aggregation of them leading to neuronal death. In the case of Alzheimer’s disease, a significant number of proteins like amyloid beta and tau seem to form unordered and problematic structures, leading through unknown mechanisms to pathological conditions and implications. Additionally, few studies have already shown the possibility of composing music sculptures retrieved from biological data, either for music audience or for cases of art therapy. In this study, we use a novel algorithm in order to present complex sound sculptures based on a hypothetical computerized interaction of amyloid beta and tau. The designed algorithm is completely adjustable, regarding several sound parameters, recognizing and emphasizing common patterns between the tested proteins for the generation of acoustic stimulus to the audience, and revealing Alzheimer’s complexity and tragedy.

KW - Alzheimer’s disease

KW - Amino acids

KW - Amyloid beta protein

KW - Art therapy

KW - Music neuroscience

KW - Musical instrument digital interface

KW - Neuroscience education

KW - Tau protein

UR - https://www.scopus.com/pages/publications/85085437046

U2 - 10.1007/978-981-13-9636-6_6

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M3 - Chapter

AN - SCOPUS:85085437046

SN - 9789811396359

SP - 117

EP - 128

BT - Biological, Diagnostic and Therapeutic Advances in Alzheimer's Disease

PB - Springer Singapore

ER -

Strengthen alzheimer’s awareness through biomusic

Abstract

UN SDGs

Keywords

Access to Document

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Cite this