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Semi-Supervised Learning for Congenital Heart Disease Prediction in Fetal Echocardiography

  • Haoyu Wu
  • , Yujie Sun
  • , Zexuan Fan
  • , Xiaowu Sun
  • Xi'an Jiaotong-Liverpool University

Research output: Chapter in Book or Report/Conference proceedingConference Proceedingpeer-review

Abstract

Fetal echocardiography is widely used for prenatal congenital heart disease (CHD) screening, but automated analysis is difficult due to strong speckle noise, large view variation, and severe class imbalance. This challenge evaluates semisupervised anatomical segmentation and multi-label CHD classification, and the final ranking is a weighted combination of classification score, segmentation score, and processing time. We propose a two-stage pipeline. We first segment viewspecific cardiac structures to obtain an anatomical mask. We then perform multi-label CHD classification with a patch-andglobal framework using a self-supervised Vision Transformer backbone. The predicted mask guides region-of-interest patch sampling and provides weak conditioning features, while view-aware constraints suppress view-incompatible labels to reduce false positives. Experiments are conducted on 2,500 ultrasound slices across four standard views, with 391 slices having pixel-wise anatomical annotations and case-level labels for seven CHD types. Our method achieves an overall score of 44.14 with an F1-score of 40.77, a DSC of 77.72, and an NSD of 61.45, outperforming the official baseline (35.89 overall, 34.20 F1, 65.48 DSC, 45.55 NSD). Code is available at https://github.com/hwu918945-alt/isbi-2026-FETUS-Semi-Seg-CHDClassification.

Original languageEnglish
Title of host publicationISBI 2026 - 23rd IEEE International Symposium on Biomedical Imaging
PublisherIEEE Computer Society
ISBN (Electronic)9798331577636
DOIs
Publication statusPublished - 2026
Externally publishedYes
Event23rd IEEE International Symposium on Biomedical Imaging, ISBI 2026 - London, United Kingdom
Duration: 8 Apr 202611 Apr 2026

Publication series

NameProceedings - International Symposium on Biomedical Imaging
Volume2026-April
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Conference

Conference23rd IEEE International Symposium on Biomedical Imaging, ISBI 2026
Country/TerritoryUnited Kingdom
CityLondon
Period8/04/2611/04/26

Keywords

  • congenital heart disease
  • fetal ultrasound
  • multi-label classification
  • semi-supervised segmentation
  • vision transformer

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