Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation

Xiushuang Yuan; Linhai Jiang; Weike Chen; Bo Song; Wei Chen; Xiaobing Zuo; Xiankai Sun; Xiaopeng Li; Kent Kirshenbaum; Shizhong Luo; He Dong

doi:10.1039/d0cc02066d

Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation

Xiushuang Yuan
, Linhai Jiang
, Weike Chen
, Bo Song
, Wei Chen
, Xiaobing Zuo
, Xiankai Sun
, Xiaopeng Li
, Kent Kirshenbaum
, Shizhong Luo
, He Dong^*

^*Corresponding author for this work

Beijing University of Chemical Technology
University of Texas at Arlington
New York University
University of South Florida
Argonne National Laboratory
University of Texas Southwestern Medical Center

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

This work demonstrates a self-assembling peptide strategy to form finite, molecularly defined trigonal bipyramidal-like hexamers which offer control over multivalent ligand display for enhanced tumor targeting.

Original language	English
Pages (from-to)	7128-7131
Number of pages	4
Journal	Chemical Communications
Volume	56
Issue number	52
DOIs	https://doi.org/10.1039/d0cc02066d
Publication status	Published - 4 Jul 2020
Externally published	Yes

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10.1039/d0cc02066d

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title = "Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation",

abstract = "This work demonstrates a self-assembling peptide strategy to form finite, molecularly defined trigonal bipyramidal-like hexamers which offer control over multivalent ligand display for enhanced tumor targeting.",

author = "Xiushuang Yuan and Linhai Jiang and Weike Chen and Bo Song and Wei Chen and Xiaobing Zuo and Xiankai Sun and Xiaopeng Li and Kent Kirshenbaum and Shizhong Luo and He Dong",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2020",

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doi = "10.1039/d0cc02066d",

language = "English",

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T1 - Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation

AU - Yuan, Xiushuang

AU - Jiang, Linhai

AU - Chen, Weike

AU - Song, Bo

AU - Chen, Wei

AU - Zuo, Xiaobing

AU - Sun, Xiankai

AU - Li, Xiaopeng

AU - Kirshenbaum, Kent

AU - Luo, Shizhong

AU - Dong, He

PY - 2020/7/4

Y1 - 2020/7/4

N2 - This work demonstrates a self-assembling peptide strategy to form finite, molecularly defined trigonal bipyramidal-like hexamers which offer control over multivalent ligand display for enhanced tumor targeting.

AB - This work demonstrates a self-assembling peptide strategy to form finite, molecularly defined trigonal bipyramidal-like hexamers which offer control over multivalent ligand display for enhanced tumor targeting.

UR - https://www.scopus.com/pages/publications/85087469155

U2 - 10.1039/d0cc02066d

DO - 10.1039/d0cc02066d

M3 - Article

C2 - 32458863

AN - SCOPUS:85087469155

SN - 1359-7345

VL - 56

SP - 7128

EP - 7131

JO - Chemical Communications

JF - Chemical Communications

IS - 52

ER -

Self-assembly of chimeric peptides toward molecularly defined hexamers with controlled multivalent ligand presentation

Abstract

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