Regulation of Ribosome Biogenesis during Skeletal Muscle Hypertrophy

Hyo Gun Kim; Bin Guo; Gustavo A. Nader

doi:10.1249/JES.0000000000000179

Regulation of Ribosome Biogenesis during Skeletal Muscle Hypertrophy

Hyo Gun Kim
, Bin Guo
, Gustavo A. Nader^*

^*Corresponding author for this work

Pennsylvania State University

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

An increase in ribosomal capacity is a hallmark of the hypertrophying muscle. We review evidence demonstrating that transcription of ribosomal RNA genes is necessary for the increase in ribosomal capacity, and this is critical for muscle growth in human and animal models of hypertrophy.

Original language	English
Pages (from-to)	91-97
Number of pages	7
Journal	Exercise and Sport Sciences Reviews
Volume	47
Issue number	2
DOIs	https://doi.org/10.1249/JES.0000000000000179
Publication status	Published - 1 Apr 2019
Externally published	Yes

Keywords

hypertrophy
keletal muscle
resistance exercise
ribosome biogenesis
transcription

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10.1249/JES.0000000000000179

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title = "Regulation of Ribosome Biogenesis during Skeletal Muscle Hypertrophy",

abstract = "An increase in ribosomal capacity is a hallmark of the hypertrophying muscle. We review evidence demonstrating that transcription of ribosomal RNA genes is necessary for the increase in ribosomal capacity, and this is critical for muscle growth in human and animal models of hypertrophy.",

keywords = "hypertrophy, keletal muscle, resistance exercise, ribosome biogenesis, transcription",

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AU - Kim, Hyo Gun

AU - Guo, Bin

AU - Nader, Gustavo A.

N1 - Publisher Copyright: © Lippincott Williams & Wilkins.

PY - 2019/4/1

Y1 - 2019/4/1

N2 - An increase in ribosomal capacity is a hallmark of the hypertrophying muscle. We review evidence demonstrating that transcription of ribosomal RNA genes is necessary for the increase in ribosomal capacity, and this is critical for muscle growth in human and animal models of hypertrophy.

AB - An increase in ribosomal capacity is a hallmark of the hypertrophying muscle. We review evidence demonstrating that transcription of ribosomal RNA genes is necessary for the increase in ribosomal capacity, and this is critical for muscle growth in human and animal models of hypertrophy.

KW - hypertrophy

KW - keletal muscle

KW - resistance exercise

KW - ribosome biogenesis

KW - transcription

UR - https://www.scopus.com/pages/publications/85063013271

U2 - 10.1249/JES.0000000000000179

DO - 10.1249/JES.0000000000000179

M3 - Article

C2 - 30632998

AN - SCOPUS:85063013271

SN - 0091-6331

VL - 47

SP - 91

EP - 97

JO - Exercise and Sport Sciences Reviews

JF - Exercise and Sport Sciences Reviews

IS - 2

ER -

Regulation of Ribosome Biogenesis during Skeletal Muscle Hypertrophy

Abstract

Keywords

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