No association between the USP7 gene polymorphisms and colorectal cancer in the chinese han population

Xin Li; Yang Wang; Xing Wang Li; Bao Cheng Liu; Qing Zhu Zhao; Wei Dong Li; Shi Qing Chen; Xiao Ye Huang; Feng Ping Yang; Quan Wang; Jin Fen Wang; Yan Zeng Xiao; Yi Feng Xu; Guo Yin Feng; Zhi Hai Peng; Lin He; Guang He

doi:10.7314/APJCP.2012.13.5.1749

No association between the USP7 gene polymorphisms and colorectal cancer in the chinese han population

Xin Li
, Yang Wang
, Xing Wang Li
, Bao Cheng Liu
, Qing Zhu Zhao
, Wei Dong Li
, Shi Qing Chen
, Xiao Ye Huang
, Feng Ping Yang
, Quan Wang
, Jin Fen Wang
, Yan Zeng Xiao
, Yi Feng Xu
, Guo Yin Feng
, Zhi Hai Peng^*
, Lin He
, Guang He

^*Corresponding author for this work

Shanghai Jiao Tong University
CAS - Shanghai Institute of Nutrition and Health
Fudan University
Shanxi Cancer Hospital

Research output: Contribution to journal › Article › peer-review

Abstract

Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.

Original language	English
Pages (from-to)	1749-1752
Number of pages	4
Journal	Asian Pacific Journal of Cancer Prevention
Volume	13
Issue number	5
DOIs	https://doi.org/10.7314/APJCP.2012.13.5.1749
Publication status	Published - 2012
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Association
Chinese Han population
Colorectal cancer
USP7 gene

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10.7314/APJCP.2012.13.5.1749

Cite this

Li, X., Wang, Y., Li, X. W., Liu, B. C., Zhao, Q. Z., Li, W. D., Chen, S. Q., Huang, X. Y., Yang, F. P., Wang, Q., Wang, J. F., Xiao, Y. Z., Xu, Y. F., Feng, G. Y., Peng, Z. H., He, L., & He, G. (2012). No association between the USP7 gene polymorphisms and colorectal cancer in the chinese han population. Asian Pacific Journal of Cancer Prevention, 13(5), 1749-1752. https://doi.org/10.7314/APJCP.2012.13.5.1749

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title = "No association between the USP7 gene polymorphisms and colorectal cancer in the chinese han population",

abstract = "Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.",

keywords = "Association, Chinese Han population, Colorectal cancer, USP7 gene",

author = "Xin Li and Yang Wang and Li, \{Xing Wang\} and Liu, \{Bao Cheng\} and Zhao, \{Qing Zhu\} and Li, \{Wei Dong\} and Chen, \{Shi Qing\} and Huang, \{Xiao Ye\} and Yang, \{Feng Ping\} and Quan Wang and Wang, \{Jin Fen\} and Xiao, \{Yan Zeng\} and Xu, \{Yi Feng\} and Feng, \{Guo Yin\} and Peng, \{Zhi Hai\} and Lin He and Guang He",

year = "2012",

doi = "10.7314/APJCP.2012.13.5.1749",

language = "English",

volume = "13",

pages = "1749--1752",

journal = "Asian Pacific Journal of Cancer Prevention",

issn = "1513-7368",

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}

Li, X, Wang, Y, Li, XW, Liu, BC, Zhao, QZ, Li, WD, Chen, SQ, Huang, XY, Yang, FP, Wang, Q, Wang, JF, Xiao, YZ, Xu, YF, Feng, GY, Peng, ZH, He, L & He, G 2012, 'No association between the USP7 gene polymorphisms and colorectal cancer in the chinese han population', Asian Pacific Journal of Cancer Prevention, vol. 13, no. 5, pp. 1749-1752. https://doi.org/10.7314/APJCP.2012.13.5.1749

TY - JOUR

T1 - No association between the USP7 gene polymorphisms and colorectal cancer in the chinese han population

AU - Li, Xin

AU - Wang, Yang

AU - Li, Xing Wang

AU - Liu, Bao Cheng

AU - Zhao, Qing Zhu

AU - Li, Wei Dong

AU - Chen, Shi Qing

AU - Huang, Xiao Ye

AU - Yang, Feng Ping

AU - Wang, Quan

AU - Wang, Jin Fen

AU - Xiao, Yan Zeng

AU - Xu, Yi Feng

AU - Feng, Guo Yin

AU - Peng, Zhi Hai

AU - He, Lin

AU - He, Guang

PY - 2012

Y1 - 2012

N2 - Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.

AB - Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.

KW - Association

KW - Chinese Han population

KW - Colorectal cancer

KW - USP7 gene

UR - https://www.scopus.com/pages/publications/84872688274

U2 - 10.7314/APJCP.2012.13.5.1749

DO - 10.7314/APJCP.2012.13.5.1749

M3 - Article

C2 - 22901115

AN - SCOPUS:84872688274

SN - 1513-7368

VL - 13

SP - 1749

EP - 1752

JO - Asian Pacific Journal of Cancer Prevention

JF - Asian Pacific Journal of Cancer Prevention

IS - 5

ER -

No association between the USP7 gene polymorphisms and colorectal cancer in the chinese han population

Abstract

UN SDGs

Keywords

Access to Document

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