Nickel-Catalyzed Asymmetric Reductive Arylation of α‑Amino-CF3 Acetates: A Strategy for the Enantioselective Synthesis of α‑Trifluoromethyl Amines Derivatives

Xue Chen; Yanran Yang; Shuli Li; Tianhao  Chen; Hegui Gong; Xiaotai Wang; Weichen Huang

doi:10.1021/acscatal.5c06406

Nickel-Catalyzed Asymmetric Reductive Arylation of α‑Amino-CF3 Acetates: A Strategy for the Enantioselective Synthesis of α‑Trifluoromethyl Amines Derivatives

Xue Chen
, Yanran Yang
, Shuli Li
, Tianhao Chen
, Hegui Gong^*
, Xiaotai Wang^*
, Weichen Huang^*

^*Corresponding author for this work

Department of Chemistry and Materials Science

Xi'an Jiaotong‐Liverpool University

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Original language	English
Pages (from-to)	17558−17567
Number of pages	10
Journal	ACS Catalysis
Volume	15
DOIs	https://doi.org/10.1021/acscatal.5c06406
Publication status	Published - 7 Oct 2025

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10.1021/acscatal.5c06406

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title = "Nickel-Catalyzed Asymmetric Reductive Arylation of α‑Amino-CF3 Acetates: A Strategy for the Enantioselective Synthesis of α‑Trifluoromethyl Amines Derivatives",

author = "Xue Chen and Yanran Yang and Shuli Li and Tianhao Chen and Hegui Gong and Xiaotai Wang and Weichen Huang",

year = "2025",

month = oct,

day = "7",

doi = "10.1021/acscatal.5c06406",

language = "English",

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pages = "17558−17567",

journal = "ACS Catalysis",

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T1 - Nickel-Catalyzed Asymmetric Reductive Arylation of α‑Amino-CF3 Acetates: A Strategy for the Enantioselective Synthesis of α‑Trifluoromethyl Amines Derivatives

AU - Chen, Xue

AU - Yang, Yanran

AU - Li, Shuli

AU - Chen, Tianhao

AU - Gong, Hegui

AU - Wang, Xiaotai

AU - Huang, Weichen

PY - 2025/10/7

Y1 - 2025/10/7

U2 - 10.1021/acscatal.5c06406

DO - 10.1021/acscatal.5c06406

M3 - Article

SN - 2155-5435

VL - 15

SP - 17558−17567

JO - ACS Catalysis

JF - ACS Catalysis

ER -