Intraperitoneal injection as a method of psychotropic drug delivery in adult zebrafish

Adam Stewart; Jonathan M. Cachat; Christopher Suciu; Peter C. Hart; Siddharth Gaikwad; Eli Utterback; John Dileo; Allan V. Kalueff

doi:10.1007/978-1-60761-953-6_14

Intraperitoneal injection as a method of psychotropic drug delivery in adult zebrafish

Adam Stewart
, Jonathan M. Cachat
, Christopher Suciu
, Peter C. Hart
, Siddharth Gaikwad
, Eli Utterback
, John Dileo
, Allan V. Kalueff

Tulane University

Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review

23 Citations (Scopus)

Abstract

Zebrafish behavioral phenotypes are often evaluated in response to pharmacological modulation by various psychotropic drugs. An important step in this process is the method of drug administration. While the most popular drug administration technique in zebrafish research is by immersion, systemic intraperitoneal injection is another effective alternative. This method is useful for drugs that are difficult to dissolve in water, or which require a better control over the amount of drug delivered to an individual animal. Here we outline a simple protocol for the intraperitoneal injection of drugs in adult zebrafish.

Original language	English
Title of host publication	Zebrafish Neurobehavioral Protocols
Editors	Allan Kalueff, Jonathan Cachat
Pages	169-179
Number of pages	11
DOIs	https://doi.org/10.1007/978-1-60761-953-6_14
Publication status	Published - 2011
Externally published	Yes

Publication series

Name	Neuromethods
Volume	51
ISSN (Print)	0893-2336
ISSN (Electronic)	1940-6045

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

anxiety
drug administration method
drug exposure
intraperitoneal injection
Zebrafish

Access to Document

10.1007/978-1-60761-953-6_14

Cite this

@inbook{b11cf35a8dcb41918fd0451125794345,

title = "Intraperitoneal injection as a method of psychotropic drug delivery in adult zebrafish",

abstract = "Zebrafish behavioral phenotypes are often evaluated in response to pharmacological modulation by various psychotropic drugs. An important step in this process is the method of drug administration. While the most popular drug administration technique in zebrafish research is by immersion, systemic intraperitoneal injection is another effective alternative. This method is useful for drugs that are difficult to dissolve in water, or which require a better control over the amount of drug delivered to an individual animal. Here we outline a simple protocol for the intraperitoneal injection of drugs in adult zebrafish.",

keywords = "anxiety, drug administration method, drug exposure, intraperitoneal injection, Zebrafish",

author = "Adam Stewart and Cachat, \{Jonathan M.\} and Christopher Suciu and Hart, \{Peter C.\} and Siddharth Gaikwad and Eli Utterback and John Dileo and Kalueff, \{Allan V.\}",

year = "2011",

doi = "10.1007/978-1-60761-953-6\_14",

language = "English",

isbn = "9781607619529",

series = "Neuromethods",

pages = "169--179",

editor = "Allan Kalueff and Jonathan Cachat",

booktitle = "Zebrafish Neurobehavioral Protocols",

}

TY - CHAP

T1 - Intraperitoneal injection as a method of psychotropic drug delivery in adult zebrafish

AU - Stewart, Adam

AU - Cachat, Jonathan M.

AU - Suciu, Christopher

AU - Hart, Peter C.

AU - Gaikwad, Siddharth

AU - Utterback, Eli

AU - Dileo, John

AU - Kalueff, Allan V.

PY - 2011

Y1 - 2011

N2 - Zebrafish behavioral phenotypes are often evaluated in response to pharmacological modulation by various psychotropic drugs. An important step in this process is the method of drug administration. While the most popular drug administration technique in zebrafish research is by immersion, systemic intraperitoneal injection is another effective alternative. This method is useful for drugs that are difficult to dissolve in water, or which require a better control over the amount of drug delivered to an individual animal. Here we outline a simple protocol for the intraperitoneal injection of drugs in adult zebrafish.

AB - Zebrafish behavioral phenotypes are often evaluated in response to pharmacological modulation by various psychotropic drugs. An important step in this process is the method of drug administration. While the most popular drug administration technique in zebrafish research is by immersion, systemic intraperitoneal injection is another effective alternative. This method is useful for drugs that are difficult to dissolve in water, or which require a better control over the amount of drug delivered to an individual animal. Here we outline a simple protocol for the intraperitoneal injection of drugs in adult zebrafish.

KW - anxiety

KW - drug administration method

KW - drug exposure

KW - intraperitoneal injection

KW - Zebrafish

UR - https://www.scopus.com/pages/publications/78149314213

U2 - 10.1007/978-1-60761-953-6_14

DO - 10.1007/978-1-60761-953-6_14

M3 - Chapter

AN - SCOPUS:78149314213

SN - 9781607619529

T3 - Neuromethods

SP - 169

EP - 179

BT - Zebrafish Neurobehavioral Protocols

A2 - Kalueff, Allan

A2 - Cachat, Jonathan

ER -

Intraperitoneal injection as a method of psychotropic drug delivery in adult zebrafish

Abstract

Publication series

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this