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Intelligent Diagnosis Using Dual-Branch Attention Network for Rare Thyroid Carcinoma Recognition with Ultrasound Imaging

  • Peiqi Li
  • , Yincheng Gao
  • , Renxing Li
  • , Haojie Yang
  • , Yunyun Liu
  • , Boji Liu
  • , Jiahui Ni
  • , Ying Zhang
  • , Yulu Wu
  • , Xiaowei Fang
  • , Lehang Guo*
  • , Liping Sun*
  • , Jiangang Chen*
  • *Corresponding author for this work
  • Department of Mathematical Sciences, University of Liverpool
  • Shanghai Key Laboratory of Multidimensional Information Processing, East China Normal University
  • Department of Ultrasound, Shanghai Tenth People's Hospital
  • Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment, Tongji University School of Medicine
  • School of Mathematics and Physics, Xi'an Jiaotong-Liverpool University

Research output: Contribution to journalArticle

Abstract

Heterogeneous morphological features and data imbalance pose significant challenges in rare thyroid carcinoma classification using ultrasound imaging. To address this issue, we propose a novel multitask learning framework, Channel-Spatial Attention Synergy Network (CSASN), which integrates a dual-branch feature extractor - combining EfficientNet for local spatial encoding and ViT for global semantic modeling, with a cascaded channel-spatial attention refinement module. A residual multiscale classifier and dynamically weighted loss function further enhance classification stability and accuracy. Trained on a multicenter dataset comprising more than 2000 patients from four clinical institutions, our framework leverages a residual multiscale classifier and dynamically weighted loss function to enhance classification stability and accuracy. Extensive ablation studies demonstrate that each module contributes significantly to model performance, particularly in recognizing rare subtypes such as FTC and MTC carcinomas. Experimental results show that CSASN outperforms existing single-stream CNN or Transformer-based models, achieving a superior balance between precision and recall under class-imbalanced conditions. This framework provides a promising strategy for AI-assisted thyroid cancer diagnosis.
Original languageEnglish
JournalarXiv preprint
DOIs
Publication statusSubmitted - 4 May 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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