Highly sensitive and stable zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) glucose biosensor

Haiyan Wu; Chen-Jung Lee; Huifeng Wang; Yang Hu; Megan Young; Yu Han; Fu-Jian Xu; Hongbo Cong; Gang Cheng

doi:10.1039/C7SC05104B

Highly sensitive and stable zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) glucose biosensor

Haiyan Wu, Chen-Jung Lee, Huifeng Wang, Yang Hu, Megan Young, Yu Han, Fu-Jian Xu, Hongbo Cong, Gang Cheng

Research output: Contribution to journal › Article › peer-review

63 Citations (Scopus)

Abstract

A zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT)-based glucose biosensor was fabricated via encapsulating glucose oxidase (GOx) in a one-step electropolymerization method. Integrating conductivity and hydrophilic properties, PSBEDOT provides a great framework for GOx immobilization and stabilization. The anti-fouling, high-sensitivity, and long-term stability properties of PSBEDOT–GOx make it a promising platform for long-term and continuous glucose monitoring.

Original language	English
Pages (from-to)	2540-2546
Number of pages	7
Journal	Chemical Science
Volume	9
Issue number	9
DOIs	https://doi.org/10.1039/C7SC05104B
Publication status	Published - 24 Jan 2018
Externally published	Yes

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title = "Highly sensitive and stable zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) glucose biosensor",

abstract = "A zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT)-based glucose biosensor was fabricated via encapsulating glucose oxidase (GOx) in a one-step electropolymerization method. Integrating conductivity and hydrophilic properties, PSBEDOT provides a great framework for GOx immobilization and stabilization. The anti-fouling, high-sensitivity, and long-term stability properties of PSBEDOT–GOx make it a promising platform for long-term and continuous glucose monitoring.",

author = "Haiyan Wu and Chen-Jung Lee and Huifeng Wang and Yang Hu and Megan Young and Yu Han and Fu-Jian Xu and Hongbo Cong and Gang Cheng",

year = "2018",

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doi = "10.1039/C7SC05104B",

language = "English",

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T1 - Highly sensitive and stable zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) glucose biosensor

AU - Wu, Haiyan

AU - Lee, Chen-Jung

AU - Wang, Huifeng

AU - Hu, Yang

AU - Young, Megan

AU - Han, Yu

AU - Xu, Fu-Jian

AU - Cong, Hongbo

AU - Cheng, Gang

PY - 2018/1/24

Y1 - 2018/1/24

N2 - A zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT)-based glucose biosensor was fabricated via encapsulating glucose oxidase (GOx) in a one-step electropolymerization method. Integrating conductivity and hydrophilic properties, PSBEDOT provides a great framework for GOx immobilization and stabilization. The anti-fouling, high-sensitivity, and long-term stability properties of PSBEDOT–GOx make it a promising platform for long-term and continuous glucose monitoring.

AB - A zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT)-based glucose biosensor was fabricated via encapsulating glucose oxidase (GOx) in a one-step electropolymerization method. Integrating conductivity and hydrophilic properties, PSBEDOT provides a great framework for GOx immobilization and stabilization. The anti-fouling, high-sensitivity, and long-term stability properties of PSBEDOT–GOx make it a promising platform for long-term and continuous glucose monitoring.

U2 - 10.1039/C7SC05104B

DO - 10.1039/C7SC05104B

M3 - Article

SN - 2041-6520

VL - 9

SP - 2540

EP - 2546

JO - Chemical Science

JF - Chemical Science

IS - 9

ER -

Highly sensitive and stable zwitterionic poly(sulfobetaine-3,4-ethylenedioxythiophene) (PSBEDOT) glucose biosensor

Abstract

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