From Soft Self-Healing Gels to Stiff Films in Suckerin-Based Materials Through Modulation of Crosslink Density and β-Sheet Content

Dawei Ding; Paul A. Guerette; Jing Fu; Lihong Zhang; Scott A. Irvine; Ali Miserez

doi:10.1002/adma.201500280

From Soft Self-Healing Gels to Stiff Films in Suckerin-Based Materials Through Modulation of Crosslink Density and β-Sheet Content

Dawei Ding, Paul A. Guerette, Jing Fu, Lihong Zhang, Scott A. Irvine, Ali Miserez^*

^*Corresponding author for this work

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

79 Citations (Scopus)

Abstract

Suckerins are block-copolymer-like structural proteins constituting the building blocks of the strong squid sucker-ring teeth. Here, recombinant suckerin-19 is processed into biomaterials spanning a wide range of elasticity, from very soft hydrogels to stiff films with elastic modulus in the gigapascal range. The elasticity is controlled by the interplay between the β-sheet content and induced di-tyrosine crosslinking.

Original language	English
Pages (from-to)	3953-3961
Number of pages	9
Journal	Advanced Materials
Volume	27
Issue number	26
DOIs	https://doi.org/10.1002/adma.201500280
Publication status	Published - 1 Jul 2015
Externally published	Yes

Keywords

crosslinks
di-tyrosine
hydrogels and films
suckerin
β-sheets

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10.1002/adma.201500280

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title = "From Soft Self-Healing Gels to Stiff Films in Suckerin-Based Materials Through Modulation of Crosslink Density and β-Sheet Content",

abstract = "Suckerins are block-copolymer-like structural proteins constituting the building blocks of the strong squid sucker-ring teeth. Here, recombinant suckerin-19 is processed into biomaterials spanning a wide range of elasticity, from very soft hydrogels to stiff films with elastic modulus in the gigapascal range. The elasticity is controlled by the interplay between the β-sheet content and induced di-tyrosine crosslinking.",

keywords = "crosslinks, di-tyrosine, hydrogels and films, suckerin, β-sheets",

author = "Dawei Ding and Guerette, \{Paul A.\} and Jing Fu and Lihong Zhang and Irvine, \{Scott A.\} and Ali Miserez",

note = "Publisher Copyright: {\textcopyright} 2015 Wiley-VCH Verlag GmbH \& Co. KGaA.",

year = "2015",

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AU - Ding, Dawei

AU - Guerette, Paul A.

AU - Fu, Jing

AU - Zhang, Lihong

AU - Irvine, Scott A.

AU - Miserez, Ali

PY - 2015/7/1

Y1 - 2015/7/1

N2 - Suckerins are block-copolymer-like structural proteins constituting the building blocks of the strong squid sucker-ring teeth. Here, recombinant suckerin-19 is processed into biomaterials spanning a wide range of elasticity, from very soft hydrogels to stiff films with elastic modulus in the gigapascal range. The elasticity is controlled by the interplay between the β-sheet content and induced di-tyrosine crosslinking.

AB - Suckerins are block-copolymer-like structural proteins constituting the building blocks of the strong squid sucker-ring teeth. Here, recombinant suckerin-19 is processed into biomaterials spanning a wide range of elasticity, from very soft hydrogels to stiff films with elastic modulus in the gigapascal range. The elasticity is controlled by the interplay between the β-sheet content and induced di-tyrosine crosslinking.

KW - crosslinks

KW - di-tyrosine

KW - hydrogels and films

KW - suckerin

KW - β-sheets

UR - https://www.scopus.com/pages/publications/84936089270

U2 - 10.1002/adma.201500280

DO - 10.1002/adma.201500280

M3 - Article

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AN - SCOPUS:84936089270

SN - 0935-9648

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JO - Advanced Materials

JF - Advanced Materials

IS - 26

ER -

From Soft Self-Healing Gels to Stiff Films in Suckerin-Based Materials Through Modulation of Crosslink Density and β-Sheet Content

Abstract

Keywords

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