Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A)

Yicheng Ding; Berta Marcó de la Cruz; Veronica McInerney; Yin Lu; Guangming Yang; Xiaohong Qian; Weidong Li; Janusz Krawczyk; Linda Howard; Timothy O'Brien; Louise Gallagher; Sanbing Shen

doi:10.1016/j.scr.2020.102101

Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A)

Yicheng Ding
, Berta Marcó de la Cruz
, Veronica McInerney
, Yin Lu
, Guangming Yang
, Xiaohong Qian
, Weidong Li
, Janusz Krawczyk
, Linda Howard
, Timothy O'Brien
, Louise Gallagher^*
, Sanbing Shen

^*Corresponding author for this work

University of Galway
Nanjing University of Chinese Medicine
National Center for Protein Sciences (Beijing)
Shanghai Jiao Tong University
Trinity College Dublin
Royal College of Surgeons in Ireland

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

The induced pluripotent stem cell (iPSC) technology has offered an unprecedented opportunity for disease modelling and drug discovery. Here we used non-integrating Sendai viral method and derived iPSCs from three young healthy Caucasian donors. All iPSCs expressed pluripotency markers highly and could be differentiated into three germ lineages. They possess normal karyotype which was confirmed by whole genome SNP array. The availability of the healthy control iPSCs offers an opportunity for phenotypic comparison and genome editing for a variety of diseases.

Original language	English
Article number	102101
Journal	Stem Cell Research
Volume	49
DOIs	https://doi.org/10.1016/j.scr.2020.102101
Publication status	Published - Dec 2020
Externally published	Yes

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title = "Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A)",

abstract = "The induced pluripotent stem cell (iPSC) technology has offered an unprecedented opportunity for disease modelling and drug discovery. Here we used non-integrating Sendai viral method and derived iPSCs from three young healthy Caucasian donors. All iPSCs expressed pluripotency markers highly and could be differentiated into three germ lineages. They possess normal karyotype which was confirmed by whole genome SNP array. The availability of the healthy control iPSCs offers an opportunity for phenotypic comparison and genome editing for a variety of diseases.",

author = "Yicheng Ding and \{de la Cruz\}, \{Berta Marc{\'o}\} and Veronica McInerney and Yin Lu and Guangming Yang and Xiaohong Qian and Weidong Li and Janusz Krawczyk and Linda Howard and Timothy O'Brien and Louise Gallagher and Sanbing Shen",

note = "Publisher Copyright: {\textcopyright} 2020 The Authors",

year = "2020",

month = dec,

doi = "10.1016/j.scr.2020.102101",

language = "English",

volume = "49",

journal = "Stem Cell Research",

issn = "1873-5061",

}

TY - JOUR

T1 - Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A)

AU - Ding, Yicheng

AU - de la Cruz, Berta Marcó

AU - McInerney, Veronica

AU - Lu, Yin

AU - Yang, Guangming

AU - Qian, Xiaohong

AU - Li, Weidong

AU - Krawczyk, Janusz

AU - Howard, Linda

AU - O'Brien, Timothy

AU - Gallagher, Louise

AU - Shen, Sanbing

PY - 2020/12

Y1 - 2020/12

N2 - The induced pluripotent stem cell (iPSC) technology has offered an unprecedented opportunity for disease modelling and drug discovery. Here we used non-integrating Sendai viral method and derived iPSCs from three young healthy Caucasian donors. All iPSCs expressed pluripotency markers highly and could be differentiated into three germ lineages. They possess normal karyotype which was confirmed by whole genome SNP array. The availability of the healthy control iPSCs offers an opportunity for phenotypic comparison and genome editing for a variety of diseases.

AB - The induced pluripotent stem cell (iPSC) technology has offered an unprecedented opportunity for disease modelling and drug discovery. Here we used non-integrating Sendai viral method and derived iPSCs from three young healthy Caucasian donors. All iPSCs expressed pluripotency markers highly and could be differentiated into three germ lineages. They possess normal karyotype which was confirmed by whole genome SNP array. The availability of the healthy control iPSCs offers an opportunity for phenotypic comparison and genome editing for a variety of diseases.

UR - https://www.scopus.com/pages/publications/85097563980

U2 - 10.1016/j.scr.2020.102101

DO - 10.1016/j.scr.2020.102101

M3 - Article

C2 - 33370872

AN - SCOPUS:85097563980

SN - 1873-5061

VL - 49

JO - Stem Cell Research

JF - Stem Cell Research

M1 - 102101

ER -

Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A)

Abstract

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