Abstract
Parkinson's disease (PD) is a progressive neurodegenerative disorder that exerts a huge burden on our society. The occurrence of this neurodegenerative disease has been increasing day-by-day. PD can be a serious concern if the patients are left untreated. However, conventional treatment has many side-effects and less bioavailability in the brain. Therefore, the necessary measurement is required to solve the limitations of PD treatment. Nanotechnology has made a major contribution to comprehend PD pathogenesis. Nanotechnology can provide efficient therapies that have reduced side-effects and increased bioavailability in the brain. This review emphasizes the emerging promise of nanoparticle-based treatment, drug delivery, and other therapeutic approaches for PD. Besides, the advantages of different approaches on nanotechnology platforms are far better over conventional therapy in the treatment of PD.
| Original language | English |
|---|---|
| Pages (from-to) | 550-560 |
| Number of pages | 11 |
| Journal | Current Drug Metabolism |
| Volume | 22 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 2021 |
| Externally published | Yes |
Keywords
- blood-brain barrier.
- nanoparticles
- nanotechnology
- Parkinson's disease
- progressive neurodegenerative disorder
- α-synuclein
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