CMB-net: a deep convolutional neural network for diagnosis of cerebral microbleeds

Cerebral microbleed (CMB) is related to cerebral vascular diseases. In this paper, we propose the use of deep convolutional neural network to implement CMB automatic diagnosis based on brain susceptibility-weighted images (SWIs). First of all, a sliding neighborhood method was employed to get 13,031 samples for training and testing. Then, an 18-layer CMB-Net was designed to classify the samples as CMB or non-CMB. The CMB-Net was trained by RMSprop based on the five-fold cross- validation. The total running time of the five-fold cross-validation was merely 184.79 s, and the average testing accuracy reached 98.39%, which was better than several recently published methods. The results suggested that our CMB-Net was accurate in detecting CMB.