Abstract
This paper provides a literature and patent review on the research and development work contributing to the current status of microsphere generation as an application of nanofluids for drug delivery. The polymer-based microsphere plays an important role to protect protein-based drugs and to deliver the drug to the desired sites. This review covers four microfluidic systems for microsphere generation: membrane emulsification with cross flow, T-junction, hydrodynamic flow focusing and chopper. A discussion on the current state of the arts of the microfluidic systems is addressed, and opportunities for future research are acknowledged.
| Original language | English |
|---|---|
| Pages (from-to) | 133-152 |
| Number of pages | 20 |
| Journal | Recent Patents on Nanotechnology |
| Volume | 7 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2013 |
| Externally published | Yes |
Keywords
- MEMS
- Microfluidic systems
- Microsphere generation
- Nanofluids