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Application of efficient nanoparticles for early diagnosis and treatment of cancer

  • Athanasios Alexiou*
  • , Charalampos Vairaktarakis
  • , Vasilis Tsiamis
  • , Ghulam Md Ashraf
  • *Corresponding author for this work
  • Ionian University
  • University of Thessaly
  • King Fahd Medical Research Center (GMA)
  • King Abdulaziz University

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

Cancer is considered as a prevalent cause of human deaths and undoubtedly, is the most complex disease with multiple cellular physiological systems involved. During the last decade, the application of nanotechnological products for cancer treatment has received considerable attention. These sophisticated tools and materials treat cancer though the early diagnosis, the prediction, the prevention and the personalized therapy. This technology enabled the development of nanoscale particles that can be conjugated with one or multiple functional molecules simultaneously. Nanoparticles have the capability to be delivered directly through blood vessels to the tumor site and interact with targeted tumor-specific proteins located inside or on the surface of cancer cells, since their size is a hundred to thousand times smaller than cancer cells. In this review, comprehensive outline of all the latest scientific and technological applications such as quantum dots and gold nanoparticles alongside with their applications in cancer diagnosis and treatment have been presented.

Original languageEnglish
Pages (from-to)662-675
Number of pages14
JournalCurrent Drug Metabolism
Volume16
Issue number8
DOIs
Publication statusPublished - 1 Sept 2015
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cancer diagnosis and treatment
  • Drug delivery
  • Gold nanoparticles
  • Nanomedicine
  • Quantum dots

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