A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein

Xiuxiu Yang; Haiyu Li; Xiaofang Zhao; Wei Liao; Claire Xi Zhang; Zhongqiang Yang

doi:10.1039/d0cc01025a

A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein

Xiuxiu Yang
, Haiyu Li
, Xiaofang Zhao
, Wei Liao
, Claire Xi Zhang^*
, Zhongqiang Yang

^*Corresponding author for this work

Tsinghua University
Capital Medical University

Research output: Contribution to journal › Article › peer-review

69 Citations (Scopus)

Abstract

A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.

Original language	English
Pages (from-to)	5441-5444
Number of pages	4
Journal	Chemical Communications
Volume	56
Issue number	40
DOIs	https://doi.org/10.1039/d0cc01025a
Publication status	Published - 18 May 2020
Externally published	Yes

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title = "A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein",

abstract = "A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.",

author = "Xiuxiu Yang and Haiyu Li and Xiaofang Zhao and Wei Liao and Zhang, \{Claire Xi\} and Zhongqiang Yang",

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AU - Yang, Xiuxiu

AU - Li, Haiyu

AU - Zhao, Xiaofang

AU - Liao, Wei

AU - Zhang, Claire Xi

AU - Yang, Zhongqiang

N1 - Publisher Copyright: © The Royal Society of Chemistry 2020.

PY - 2020/5/18

Y1 - 2020/5/18

N2 - A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.

AB - A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.

UR - https://www.scopus.com/pages/publications/85084939687

U2 - 10.1039/d0cc01025a

DO - 10.1039/d0cc01025a

M3 - Article

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VL - 56

SP - 5441

EP - 5444

JO - Chemical Communications

JF - Chemical Communications

IS - 40

ER -

A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein

Abstract

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