Personal profile
Personal profile
Ziwen Xie graduated from the XJTLU/University of Liverpool and carried out further research at the Imperial College, London, followed by 5 years of working as laboratory technician in Department of Biological Sciences in XJTLU, and start PhD journey until 2024. His research focuses on the Mycobacteria protein function study for further potential drug target identifcation He has authored 2 publications. He has support supervised one PhD student, more than 10 master students and more than 20 undergraduated students in XJTLU as a technician or teaching assistant during PhD journey. He has served as an experimental consultant for XJTLU iGEM team for 6 years, contributing to the team's consecutive gold awards in 4 years. After PhD, he continued to work as a senior technician in the Department of Bioscience and Bioinformatics.
Research interests
- Mycobacteria protein crystallyzation and enzyme activity
- Mycobacteria protein function in cell wall and menaquinone biosynthesis
- Potential drug target in Mycobacterium tuberculosis
Experience
- Senior (Biology) Technician, Department of Biosciences and Bioinformatics, XJTLU - Since 01/2025
- PhD of Science in Biological Sciences, School of Science, XJTLU - 12/2019 - 09/2024
- Experimental consultant for XJTLU iGEM team - 10/2019 - 10/2024
- Laboratory (Biology) Technician, Biological Sciences, XJTLU - 01/2015 - 11/2019
- Part-time Laboratory Technician in Biological Sciences, National pear research center, Nanjing Agricultural University - 06/2013 - 08/2013
- Part-time Laboratory assistant, Suzhou GoodeePHarama Co.Ltd - 06/2010 - 08/2010
Teaching
- BIO113 - Molecular Biology Techniques (2022-23 to Present; TAs Leader)
- BIO202 - Advanced Biochemical Methods (2020-22, 2022-2023; TAs Leader)
- BIO204 - Advanced Genetics (2021-23; TAs Leader)
- BIO205 - Molecular and Cell Biology Techniques (2021-23; TAs Leader)
- BIO401 - Research Method in Biotechnology, MRes Molecular Bioscience (2020 to 2022, TA)
Awards and honours
- iGEM Gold Medal, Top 10 in the undergraduate group, first place in the Special Award for New Composite Part, nomination for the Special Award for Best Wiki, nomination for the Track Award for Oncology – Team XJTLU-Science-CHINA (Instructor) (2025).
- iGEM Silver Medal - Team XJTLU-AI-CHINA (Instructor) (2025)
- iGEM Bromze Medal – Team XJTLU-CHINA (Advisor) (2024).
- Teaching Assistant Award - XJTLU 2024 Academic Excellence Awards (2024).
- iGEM Gold Medal – Team XJTLU-CHINA (Advisor) (2023).
- Excellent Oral Presentation Award - XJTLU postgraudate research symposium, XJTLU, China (2022)
- iGEM Gold Medal – Team XJTLU-CHINA (Instructor) (2022).
- Best Poster Award - XJTLU postgraudate research symposium, XJTLU, China (2021).
- iGEM Gold Medal – Team XJTLU-CHINA (Instructor) (2021).
- In the program:
J. Meng, X. Cui, S.J. Gao, R. Rong, F. Gao, Z. Xie and D. Carrillio, Bioinformatics approaches for RNA methylation-related high-throughput sequencing data and RNA methylome regulatory network reconstruction (RNA甲基化修饰高通量测序数据的生物信息方法开发以及RNA甲基化修饰调控网络的系统重建), National Natural Science Foundation of China, General Program (国家自然科学基金面上项目), 31671373, 570k RMB, (2017 - 2020). - XJTLU Outstanding Student for 2010-2011 Academic year (2011).
Education/Academic qualification
PhD, Involvement of the essential gene MSMEG_1353 in cell envelope biosynthesis pathways of Mycolicibacterium smegmatis, XJTLU
1 Dec 2019 → 1 Sept 2024
Award Date: 1 Sept 2024
Master, MSc of Molecular plant and microbiology technology, Imperial Colleage London
Sept 2013 → Sept 2014
Award Date: 24 Sept 2014
Bachelor, BSc of Microbiology, School of Biology Science, University of Liverpool
Sept 2011 → Jun 2013
Award Date: 1 Jun 2013
Undergraduate, BSc of Biological Sciences, Department of Biological Science, XJTLU
Sept 2009 → Jun 2011
Keywords
- Q Science (General)
Person Types
- Staff
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Impairment of two non-essential LytR-cpsA-psr (Lcp) cell wall ligases decelerate cell wall assembly in Mycolicibacterium smegmatis
Sahu, A., Xie, Z., Cheng, H. J., Omoboyowa, D. A., Zhang, L., Zhai, X. C., Bitter, W., Ruiz-Carrillo, D., Tefsen, B., Li, J.-M. & Yang, Y., 23 Jan 2026, In: BMC Microbiology.Research output: Contribution to journal › Article › peer-review
Open Access -
Linking MSMEG_1353 to lipid metabolism and envelope integrity in Mycolicibacterium smegmatis
Xie, Z., Lioe, T. S., Sahu, A., Cui, J., Ruiz Carrillo, D., Kadowaki, T. & Tefsen, B., 2025, In: bioRxiv.Research output: Contribution to journal › Article
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实验室安全多链条信息化闭环管理研究
Xie, Z., Cui, J. & Yang, L., 2025, 江苏省高校实验室研究会成立40周年暨2025年学术年会 论文集. 江苏省高等教育学会高校实验室研究委员会Translated title of the contribution :Research on Multi-chain Information-Based Closed-loop Management of Laboratory Safety Research output: Chapter in Book or Report/Conference proceeding › Conference Proceeding › peer-review
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The Mycobacterium tuberculosis prolyl dipeptidyl peptidase cleaves the N-terminal peptide of the immunoprotein CXCL-10
Lioe, T. S., Xie, Z., Wu, J., Li, W., Sun, L., Feng, Q., Sekar, R., Tefsen, B. & Ruiz-Carrillo, D., 12 Jan 2023, In: Biological Chemistry. 404, 6, p. 633-643 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Biochemical characterization of a Mycobacterium tuberculosis prolyl dipeptidyl peptidase that displays a remarkable thermostability
Lioe, T. S., Xie, Z., Sun, L., Feng, Q., Sekar, R., Tefsen, B. & Ruiz Carrillo, D., 2022.Research output: Contribution to conference › Paper › peer-review
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PhD project 3rd year presentation
Xie, Z. (Speaker)
2023Activity: Talk or presentation › Presentation at conference/workshop/seminar
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XJTLU postgraudate research symposium
Xie, Z. (Speaker)
Dec 2022Activity: Talk or presentation › Presentation at conference/workshop/seminar
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XJTLU postgraudate research symposium
Xie, Z. (Speaker)
Dec 2021Activity: Talk or presentation › Presentation at conference/workshop/seminar
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