Dr. Shining Loo joined the Academy of Pharmacy at Xi’an Jiaotong-Liverpool University as an Assistant Professor in 2023. Dr. Loo received First-Class Honors in a Double Bachelor’s Degree in Biomedical Science and Traditional Chinese Medicine (TCM) from the Nanyang Technological University (NTU), School of Biological Sciences (SBS), Singapore, and the Beijing University of Chinese Medicine, Beijing, China. She is also a licensed practicing TCM physician in Singapore. She was awarded the prestigious Nanyang President’s Graduate Scholarship and received her Ph.D. in Biological Sciences at NTU, SBS, Singapore, under the supervision of Professor James P. Tam (2013-2018). Upon graduation, Dr. Loo was appointed as a Research Fellow and continued her postdoctoral research work with Professor Tam’s group (2018-2023).Dr. Loo’s research interests center around peptide drug discovery and their translational applications for precision medicine, theranostics, drug delivery, material, and food technologies. Dr. Loo has published over 20 peer-reviewed publications in well-recognized journals like the Journal of American Chemical Society, Angewandte Chemie International Edition, Journal of Medicinal Chemistry, Journal of Biological Chemistry, Acta Pharmaceutica Sinica B, Frontiers in Pharmacology, and Frontiers in Plant Sciences. She also holds 2 US and China national phase patent applications. In 2021, Dr. Loo won the Mistletoe Research Fellowship, the title of Mistletoe Research Fellow, and an Unfettered Research Grant from the Momental Foundation. She was also awarded the Merck Life Science Publication Award (First Prize) for her research contributions in the field of biology and biochemistry.

Led by Dr. Shining Loo (Wisdom Lake Academy of Pharmacy) and Dr. Antony Kam (Department of Biological Sciences) at Xi'an JiaoTong Liverpool University), XPad (XJTLU Peptide and Drug) is a collaborative research group at the forefront of peptide/protein-based technologies. We leverage our expertise in molecular pharmacology, synthetic biology, and chemical biology to develop innovative solutions for:

• Therapeutics: Designing next-generation drugs with targeted precision to combat various diseases.
• Diagnostics: Creating highly accurate and personalized medical tests for early disease detection and personalized treatment.
• Biomaterials: Engineering advanced materials for tissue regeneration and repair, promoting healing and improving lives.
• Drug Delivery Systems: Revolutionizing how therapeutics are delivered safely and effectively, maximizing their impact.

Shining Loo 博士于2023年加入西交利物浦大学慧湖药学院，担任助理教授。Loo 博士获得了新加坡南洋理工大学（NTU）生物科学学院（SBS）与中国北京中医药大学联合颁发的生物医学与中医学双学士（一等荣誉）学位。她也是新加坡的注册执业中医师。她曾荣获享有盛誉的南洋校长研究生奖学金（Nanyang President’s Graduate Scholarship），并在 James P. Tam 院士的指导下，于新加坡南洋理工大学生物科学学院获得生物科学博士学位（2013-2018年）。毕业后，Loo 博士被聘为研究员（Research Fellow），在 Tam 教授的团队继续从事博士后研究工作（2018-2023年）。

Loo 博士的研究兴趣主要集中在多肽与蛋白质药物的发现，及其在精准医疗、诊疗一体化、药物递送、材料科学和食品技术领域的转化应用。Loo 博士在《美国化学会志》(Journal of the American Chemical Society)、《德国应用化学》(Angewandte Chemie International Edition)、《药物化学杂志》(Journal of Medicinal Chemistry)、《生物化学杂志》(Journal of Biological Chemistry)、《药学学报》英文版 (Acta Pharmaceutica Sinica B)、《药理学前沿》(Frontiers in Pharmacology) 和《植物科学前沿》(Frontiers in Plant Sciences) 等国际知名学术期刊上发表了20多篇经同行评审的学术论文。她还拥有两项处于中美国家阶段的专利申请。2021年，Loo 博士获得了 Mistletoe 研究奖学金，被授予 Mistletoe 研究员 (Mistletoe Research Fellow) 称号，并获得了 Momental 基金会颁发的无限制研究资助 (Unfettered Research Grant)。此外，因其在生物学和生物化学领域的突出研究贡献，她还荣获了默克生命科学论文奖一等奖 (Merck Life Science Publication Award, First Prize)。

XPad（西浦多肽与药物，XJTLU Peptide and Drug）是由西交利物浦大学慧湖药学院的 Shining Loo 博士和生物科学系的 Antony Kam 博士共同领导的合作研究团队。该团队处于多肽与蛋白技术领域的前沿，充分利用在分子药理学、合成生物学和化学生物学方面的专业知识，致力于为以下领域开发创新解决方案：

• 疾病治疗 (Therapeutics)： 设计具有精准靶向性的下一代药物，以对抗各类疾病。
• 医疗诊断 (Diagnostics)： 开发高精度、个性化的医学检测方法，用于疾病的早期筛查和个性化治疗。
• 生物材料 (Biomaterials)： 研发用于组织再生和修复的先进材料，促进伤口愈合，改善人类生活质量。
• 药物递送系统 (Drug Delivery Systems)： 革新治疗药物的安全有效递送方式，以实现药效最大化。

She welcomes interested academic and industrial collaborations as well as students to join her group.Interested parties can contact via e-mail: Shining.loo@xjtlu.edu.cn

Read more about our XPad XJTLU Peptide and Drug research group!

https://connect.xjtlu.edu.cn/group/xpad

Precision Medicine

Peptide Drug Discovery and Design

Mass Spectrometry Proteomics-based Target-identification, Functional and Structural Characterization

High-throughput Drug Screening and Validation

Peptide and Protein Chemistry

Molecular Pharmacology

Targeted Protein Modifiers

Targeted Drug Delivery

Natural Products

Assistant Professor, Academy of Pharmacy, Xi’an Jiaotong-Liverpool University (2023- Present)

Research Fellow (Supervisor: Professor James P Tam), School of Biological Sciences, Nanyang Technological University, Singapore (2018-2023)

APH005 Diseases, Healthcare and Society

APH216 Drug Action

APH303 Biotechnological Pharmaceutics

XJTLU SURF 2023 Group Winner (2023)

Merck Life Science Publication Award (First Prize) (2021)

Mistletoe Research Fellowship (2021)

10th International Peptide Symposium Travel Award (JPY$ 46,000) (2018)

Women in Engineering, Science, and Technology (WiEST) Conference Grant (SGD$ 3,000) (2018)

Pharmaceuticals Travel Award (CHF$ 800) (2018)

ASBMB Graduate Travel Award (USD$ 1,000) (2018)

Peptide Therapeutics Foundation Travel Grant (USD$ 500) (2016)

Nanyang Presidents Graduate Scholarship (2013-2018)

NTU President Research Scholar (URECA) (2009-2010)