Projects per year
Personal profile
Personal profile
- Dr. Cheng joined the Academy of Pharmacy at XJTLU as an assistant professor in 2021. She has broad experience in mass spectrometry and NMR-based comprehensive metabolomics and lipidomics studies. She has also been working on biomarker discovery and patient stratification via integrated study of multi-omics data, and investigating the regulatory mechanism of bioactive compounds on health and metabolic disease risk in intervention studies.
- Contact me via email (ken.cheng@xjtlu.edu.cn), if you are interested in collaboration.
- Research key words: metabolomics, multi-omics, mass spectrometry, biomarker, bioactive compounds in natural products
Research interests
- Exploration of novel biomarkers and establishment of diagnostic and predictive models based on multiple omics data, especially metabolome, proteome and gut microbiota, and multi-dimensional data integration approaches.
- Regulatory mechanism investigation of bioactive compounds in metabolic diseases.
- Mass spectrometry-based analytical methods for comprehensive coverage of metabolome and lipidome.
Experience
- 2021-present, Assistant professor, Academy of Pharmacy, XJTLU, Suzhou
- 2021-present, Honorary Academic Staff, University of Liverpool, UK
- 2018-2021, Senior researcher, Shenzhen Digital Life Institute (iCarbonX), Shenzhen
- 2017-2018, Postdoc, Department of Food and Nutrition Science, Chalmers Institute of Technology, Goteborg, Sweden
- 2012, French translator, I-TEK, Tremeur, France
Teaching
Current modules
- APH002, Introduction to Basic Science of Medicine (module leader)
- APH211, Principle of Engineering (module leader)
- APH113, Artificial Intelligence in Healthcare & Pharmaceutical Research (co-teacher)
Previous modules
- APH001, Explore Pharmaceutical Sciences (module leader)
- APH004, Brief History of Drug Discovery (module leader)
- APH402, Modern Instrumentation Analytical Technologies (co-teacher)
- APH404, Modern Pharmaceutical Activity Screening (co-teacher)
Awards and honours
- Shenzhen Longhua Chinese Dragon Plan Talent (level A), 2019
- Shenzhen Overseas High-Caliber Personnel (level C), 2019
- The Eurofed Lipid Nordic Lipidforum Young Scientist Award, 2017
Education/Academic qualification
Bsc, Harbin Institute of Technology, Harbin, China, 2005-2009
Master, Universite de Rennes, Rennes, France, 2009-2012
PhD, Swedish University of Agricultural Science, Uppsala, Sweden, 2012-2017
Person Types
- Staff
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 14 Life Below Water -
SDG 15 Life on Land
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 5 Active
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Study on the mechanism of DMGV-induced functional impairment of pancreatic β-cell and early progression of type 2 diabetes
Cheng, K. (PI)
1/01/25 → 31/12/27
Project: Governmental Research Project
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The mechanism of ammonia accumulation promotes liver cancer progression via calcium channel-mTORC2-SREBP1-lipogenesis dependent manner
Dai, W. (PI), Wang, S. (Team member), Chen, G. (Team member), Elkord, E. (Team member), Hamada, K. (Team member), Cheng, K. (Team member), Xu, J. (Team member), Huang, S. (Team member), Yang, C. (Team member), Ma, J. (Team member) & Bin, U. (Team member)
1/01/25 → 31/12/28
Project: Governmental Research Project
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Single-Molecule Single-Cell Imaging and Analysis Innovation Platform
Ruan, G. (PI), Zhang, X. (Team member), Wang, Y. (Team member), Zhou, Z. (Team member), Zhang, J. (Team member), Ding, D. (Team member), Ling, C. (Team member), Wu, Q. (Team member), Xu, P. (Team member), Ho, J. (Team member), Cheng, K. (Team member), Song, J. (Team member), Guo, B. (Team member), Wu, S. (Team member), Wang, J. (Team member), Sun, Y. (Team member), Lu, T. (Team member), Li, T. (Team member), Xu, Y. (Team member), Huang, D. (Team member), Cao, S. (Team member), Leng, J. (Team member) & Wen, X. (Team member)
1/10/24 → 30/09/26
Project: Governmental Research Project
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Jiangsu Province Higher Education Key Laboratory of Cell Therapy Nanoformulation (Construction)
Ruan, G. (PI), Lee, M. H. (Team member), Wu, Q. (Team member), Lu, T. (Team member), Xu, P. (Team member), Loo, S. (Team member), Sun, Y. (Team member), Kam, A. (Team member), Liu, X. (Team member), Wen, X. (Team member), Zhang, J. (Team member), Wang, M. (Team member), Xu, M. (Team member), Cheng, K. (Team member), Zhang, X. (Team member), Song, J. (Team member), Guo, B. (Team member), Wang, Y. (Team member), Wang, J. (Team member), Wu, S. (Team member), Yang, J. (Team member), Fu, L. (Team member), Zhang, J. (Team member), Qiao, Y. (Team member), Chen, Y. (Team member), Li, T. (Team member), Zhan, T. (Team member), Wan, Y. (Team member), He, Z. (Team member), Cheng, Y. (Team member), Leng, J. (Team member), Qi, M. (Team member), Ho, J. (Team member), Sun, Y. (Team member), Zhang, N. (Team member), Soe, H. M. S. H. (Team member), Ling, C. (Team member), Zhou, H. (Team member), Huang, D. (Team member) & Gu, J. (Team member)
1/07/24 → 30/06/27
Project: Governmental Research Project
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The role of dimethylguanidino valeric acid (DMGV) in carbohydrate and lipid metabolism
Cheng, K. (PI), Wang, M. (Team member) & Liu, Y. (Team member)
1/09/22 → 31/08/26
Project: Internal Research Project
Research output
- 20 Article
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ACAT3 controls hepatic cholesterol metabolism and modulates systemic energy homeostasis of male mice
Ma, Z., Chen, Q., Zhang, J., Huang, Z., Wu, Q., Shi, T., Liu, X., Shu, H., Ma, Y., Cheng, K., Zhang, C., Jia, Z., Feng, Y. & Jiang, C., 15 Sept 2026, In: Life Sciences. 401, 124519.Research output: Contribution to journal › Article › peer-review
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Asymmetric dimethylguanidino valeric acid as an independently associated risk factor for early hypertriglyceridemia and dyslipidemia
Han, Y., Xiong, Q., Wang, J., Wang, A., Chen, Q., Liu, Y. & Cheng, K., 7 Mar 2026, In: Metabolomics. 22, 2, 34.Research output: Contribution to journal › Article › peer-review
Open Access -
Polygonatum kingianum polysaccharides ameliorate cognitive impairments in alcohol-exposed obese mice in a sex-specific manner by regulating the gut microbiome and metabolome
Lv, J., Qu, Y., Yan, Q., Cheng, K., Wu, Q., Zhang, J., Duan, X., Han, S., Tian, H. & Shi, L., 31 Oct 2026, In: Food Research International. 242, 119827.Research output: Contribution to journal › Article › peer-review
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PRMT3-mediated post-translational adaptation to fasting regulates metabolic flexibility
Huang, Z., Liu, X., Chen, X., Zhou, Y., Chen, Q., Liu, Y., Zhu, H., Cheng, K., Feng, Y., Dong, M., Song, L., Wang, L., Liu, S., Shan, T., Kuang, S., Dong, Y., Vidal-Puig, A., Zhang, Y. & Jia, Z., 2 Feb 2026, In: Nature Communications. 17, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Wheat Bran Arabinoxylan Potentiates Hepatoprotective Efficacy of Postbiotic Limosilactobacillus reuteri in Colitis Mice via a Gut–Liver Axis
Zhou, L., Liu, T., Zhang, S., Lv, J., Wang, Y., Wang, G., Dai, X., Wang, J., Zhang, Z., Cheng, K., Tian, H. & Shi, L., 2 Mar 2026, In: Journal of Agricultural and Food Chemistry. 74, 13Research output: Contribution to journal › Article › peer-review