Projects per year
Personal profile
Personal profile
- Dr. Cheng joined the Academy of Pharmacy at XJTLU as an assistant professor in 2021. She has broad experience in mass spectrometry and NMR-based comprehensive metabolomics and lipidomics studies. She has also been working on biomarker discovery and patient stratification via integrated study of multi-omics data, and investigating the regulatory mechanism of bioactive compounds on health and metabolic disease risk in intervention studies.
- Contact me via email (ken.cheng@xjtlu.edu.cn), if you are interested in collaboration.
- Research key words: metabolomics, multi-omics, mass spectrometry, biomarker, bioactive compounds in natural products
Research interests
- Exploration of novel biomarkers and establishment of diagnostic and predictive models based on multiple omics data, especially metabolome, proteome and gut microbiota, and multi-dimensional data integration approaches.
- Regulatory mechanism investigation of bioactive compounds in metabolic diseases.
- Mass spectrometry-based analytical methods for comprehensive coverage of metabolome and lipidome.
Experience
- 2021-present, Assistant professor, Academy of Pharmacy, XJTLU, Suzhou
- 2021-present, Honorary Academic Staff, University of Liverpool, UK
- 2018-2021, Senior researcher, Shenzhen Digital Life Institute (iCarbonX), Shenzhen
- 2017-2018, Postdoc, Department of Food and Nutrition Science, Chalmers Institute of Technology, Goteborg, Sweden
- 2012, French translator, I-TEK, Tremeur, France
Teaching
Current modules
- APH002, Introduction to Basic Science of Medicine (module leader)
- APH211, Principle of Engineering (module leader)
- APH113, Artificial Intelligence in Healthcare & Pharmaceutical Research (co-teacher)
Previous modules
- APH001, Explore Pharmaceutical Sciences (module leader)
- APH004, Brief History of Drug Discovery (module leader)
- APH402, Modern Instrumentation Analytical Technologies (co-teacher)
- APH404, Modern Pharmaceutical Activity Screening (co-teacher)
Awards and honours
- Shenzhen Longhua Chinese Dragon Plan Talent (level A), 2019
- Shenzhen Overseas High-Caliber Personnel (level C), 2019
- The Eurofed Lipid Nordic Lipidforum Young Scientist Award, 2017
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Bsc, Harbin Institute of Technology, Harbin, China, 2005-2009
Master, Universite de Rennes, Rennes, France, 2009-2012
PhD, Swedish University of Agricultural Science, Uppsala, Sweden, 2012-2017
Person Types
- Staff
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Collaborations and top research areas from the last five years
Projects
- 5 Active
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Study on the mechanism of DMGV-induced functional impairment of pancreatic β-cell and early progression of type 2 diabetes
Cheng, K. (PI)
1/01/25 → 31/12/27
Project: Governmental Research Project
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The mechanism of ammonia accumulation promotes liver cancer progression via calcium channel-mTORC2-SREBP1-lipogenesis dependent manner
Dai, W. (PI), Wang, S. (Team member), Chen, G. (Team member), Elkord, E. (Team member), Hamada, K. (Team member), Cheng, K. (Team member), Xu, J. (Team member), Huang, S. (Team member), Yang, C. (Team member), Ma, J. (Team member) & Bin, U. (Team member)
1/01/25 → 31/12/28
Project: Governmental Research Project
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Single-Molecule Single-Cell Imaging and Analysis Innovation Platform
Ruan, G. (PI), Zhang, X. (Team member), Wang, Y. (Team member), Zhou, Z. (Team member), Zhang, J. (Team member), Ding, D. (Team member), Ling, C. (Team member), Wu, Q. (Team member), Xu, P. (Team member), Ho, J. (Team member), Cheng, K. (Team member), Song, J. (Team member), Guo, B. (Team member), Wu, S. (Team member), Wang, J. (Team member), Sun, Y. (Team member), Lu, T. (Team member), Li, T. (Team member), Xu, Y. (Team member), Huang, D. (Team member), Cao, S. (Team member), Leng, J. (Team member) & Wen, X. (Team member)
1/10/24 → 30/09/26
Project: Governmental Research Project
-
Jiangsu Province Higher Education Key Laboratory of Cell Therapy Nanoformulation (Construction)
Ruan, G. (PI), Lee, M. H. (Team member), Wu, Q. (Team member), Lu, T. (Team member), Xu, P. (Team member), Loo, S. (Team member), Sun, Y. (Team member), Kam, A. (Team member), Liu, X. (Team member), Wen, X. (Team member), Zhang, J. (Team member), Wang, M. (Team member), Xu, M. (Team member), Cheng, K. (Team member), Zhang, X. (Team member), Song, J. (Team member), Guo, B. (Team member), Wang, Y. (Team member), Wang, J. (Team member), Wu, S. (Team member), Yang, J. (Team member), Fu, L. (Team member), Zhang, J. (Team member), Qiao, Y. (Team member), Chen, Y. (Team member), Li, T. (Team member), Zhan, T. (Team member), Wan, Y. (Team member), He, Z. (Team member), Cheng, Y. (Team member), Leng, J. (Team member), Qi, M. (Team member), Ho, J. (Team member), Sun, Y. (Team member), Zhang, N. (Team member), Soe, H. M. S. H. (Team member), Ling, C. (Team member), Zhou, H. (Team member), Huang, D. (Team member) & Gu, J. (Team member)
1/07/24 → 30/06/27
Project: Governmental Research Project
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The role of dimethylguanidino valeric acid (DMGV) in carbohydrate and lipid metabolism
Cheng, K. (PI), Wang, M. (Team member) & Liu, Y. (Team member)
1/09/22 → 31/08/26
Project: Internal Research Project
Research output
- 15 Article
-
A synthesis and quantification method for endogenous metabolites dimethylguanidino valeric acid
Han, Y., Wang, J., Xiong, Q., Jiang, D., Zhu, Z., Hui, L., Wang, M., Qiao, Y., Li, Y., Han, L., Liu, Y. & Cheng, K., Apr 2025, In: Scientific Reports. 15, 1, 11100.Research output: Contribution to journal › Article › peer-review
Open Access -
Milk protein modulates antioxidant activity and metabolome stability in coffee beverages during thermal processing
Chen, N., Xie, K., Jiao, Z., Zhang, W., Deng, H., Ashaolu, T. J., Cheng, K. & Zhao, C., Nov 2025, In: Journal of Dairy Science. 108, 11, p. 11919-11939 21 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Postbiotic Limosilactobacillus reuteri cultured with Polygonatum kingianum polysaccharides ameliorates high-fat-high-sugar-deteriorated colitis and associated hepatobiliary disorders
Liu, T., Lv, J., Bian, B., Wu, Q., Zhou, L., Zhang, S., Song, W., Li, X., Tian, H., Cheng, K. & Shi, L., Sept 2025, In: International Journal of Biological Macromolecules. 322, 147065.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Effects of protein on green tea quality in a milk-tea model during heat treatment: Antioxidant activity, foaming properties, and unbound small-molecule metabolome
Chen, N., Jiao, Z., Xie, K., Liu, J., Yao, P., Luo, Y., Zhang, T., Cheng, K. & Zhao, C., Dec 2024, In: Journal of Dairy Science. 107, 12, p. 10462-10480 19 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Flavonifractor plautii Protects Against Elevated Arterial Stiffness
Luo, S., Zhao, Y., Zhu, S., Liu, L., Cheng, K., Ye, B., Han, Y., Fan, J. & Xia, M., 20 Jan 2023, In: Circulation Research. 132, 2, p. 167-181 15 p.Research output: Contribution to journal › Article › peer-review
Open Access50 Citations (Scopus)