Projects per year
Personal profile
Personal profile
01/2024-present Assistant Professor, Xi’an Jiaotong Liverpool University
05/2018-12/2023 Postdoctoral Research Fellow, University of Michigan
09/2012-04/2018 Ph.D University of Michigan, Ann Arbor, MI, USA
Dr. Song joined the Academy of Pharmacy, Xi’an Jiaotong-Liverpool University as an Assistant Professor in Jan 2024.
She received her PhD in 2018 under the mentorship of Dr. Richard Mortensen at the University of Michigan, Ann Arbor, Department of Cell and Developmental Biology.
Her postdoctoral work was conducted in the Department of Internal Medicine with Dr. Daniel Goldstein. She gained her expertise in aging, immunity, adipose tissue, cardiovascular diseases (CVDs) and cancer.
Her laboratory is interested in how aging impacts immunity and immune cell metabolism in disease models including CVDs, cancer and obesity. Mechanistically, their work focuses on immunity, inflammation, aging, metabolism, adipose tissue and autophagy.
Research interests
1. Obesity promotes cancer development and progression during aging.
2. How itaconate suppresses inflammation to improve cardiovascular diseases.
3. Activate immunity through autophagy to fight against cancer with age.
4. Immune cell metabolism reprogramming in disease models like cardiovascular diseases and cancer.
Experience
Postdoctoral Research Fellow, University of Michigan, Ann Arbor USA 2018-2023
Research Assistant, Eastern Hepatobiliary Surgery Hospital, Shanghai China 2009-2012
Teaching
APH218 Principles of Pharmacology
APH202 Pharmacology
APH423 Principles of Toxicology
APH429 Research Ethics and Research Methodology
Awards and honours
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Research Development Fund (RDF-23-02-014), Mechanistic investigation about the anti-inflammatory role of itaconate in atherosclerosis, Xi’an Jiaotong Liverpool University (XJTLU), RMB 100,000, 07/01/2024- 06/30/2027. Principle Investigator.
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AHA 2022 Postdoctoral Fellowship (898210), Mechanism by which aging promotes atherogenesis via adipose inflammation, American Heart Association (AHA), USD 145,020.00, 01/01/2022-12/31/2023. Principle Investigator.
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Pandemic Research Recovery Grant (U077239), Aging promotes atherogenesis via adipose tissue inflammation, University of Michigan Medical School, 05/01/2022 – 04/30/2023. Principle Investigator.
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AHA 2015 Predoctoral Fellowship (15PRE25090080), Regulation of myeloid cell phenotypes by the mineralocorticoid receptor during stroke, American Heart Association (AHA), USD 52,000, 07/01/2015-06/30/2017. Principle Investigator.
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Bradley Merrill Patten Memorial Research Fellowship, University of Michigan Cell and Developmental Biology Department, USD 38,000, 09/2014- 09/2017. Principle Investigator.
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Rackham Graduate Student Research Grant, Rackham Graduate School of University of Michigan. May 2017. Principle Investigator.
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Shanghai Natural Science Foundation (11ZR1449500 上海市自然科学基金), The role of autophagy in adaptation and resistance of liver cancer stem cell to the ischemic microenvironment and chemotherapy. RMB 100,000, 04/01/2011-03/31/2014. Principle Investigator.
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National Natural Science Foundation of China (81101622 国自然青年项目), The role and mechanism of autophagy in the adaptation of liver cancer stem cell to the hypoxic and nutrient-deprived microenvironment in hepatocellular carcinoma. RMB 220, 000, 01/2012-12/2014. Principle Investigator.
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3rd Prize of Jiangsu Science and Technology Award, Jiangsu Provincial Peoples Government 2016
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2nd Prize of Shanghai Science and Technology Award, The Shanghai Municipal Peoples Government 2011
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The Ming K.Jeang scholarship Award, Society of Chinese Bioscientists in America 2011
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Employee of the Year, Eastern Hepatobiliary Surgery Hospital, Shanghai 2010
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Related documents
Age-associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis
Age and Sex: Impact on adipose tissue metabolism and inflammation
Age-Associated Mitochondrial Dysfunction Accelerates Atherogenesis
Aconitate decarboxylase 1 regulates glucose homeostasis and obesity in mice
http://Suzhou Municipal Key Lab for Metabolic Syndrome Drug Research
Education/Academic qualification
Ph.D, Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA 2012-2018
MMed, Oncology, Second Military Medical University, Shanghai China 2006-2009
Research areas
- Metabolic reprogramming in CVD and cancer;
- Macrophage in immune responses;
- Aging and senescence
Person Types
- Staff
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 3 Active
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Single-Molecule Single-Cell Imaging and Analysis Innovation Platform
Ruan, G. (PI), Zhang, X. (Team member), Wang, Y. (Team member), Zhou, Z. (Team member), Zhang, J. (Team member), Ding, D. (Team member), Ling, C. (Team member), Wu, Q. (Team member), Xu, P. (Team member), Ho, J. (Team member), Cheng, K. (Team member), Song, J. (Team member), Guo, B. (Team member), Wu, S. (Team member), Wang, J. (Team member), Sun, Y. (Team member), Lu, T. (Team member), Li, T. (Team member), Xu, Y. (Team member), Huang, D. (Team member), Cao, S. (Team member), Leng, J. (Team member) & Wen, X. (Team member)
1/10/24 → 30/09/26
Project: Governmental Research Project
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Mechanistic investigation about the anti-inflammatory role of itaconate in atherosclerosis
Song, J. (PI)
1/07/24 → 30/06/27
Project: Internal Research Project
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Jiangsu Province Higher Education Key Laboratory of Cell Therapy Nanoformulation (Construction)
Ruan, G. (PI), Lee, M. H. (Team member), Wu, Q. (Team member), Lu, T. (Team member), Xu, P. (Team member), Loo, S. (Team member), Sun, Y. (Team member), Kam, A. (Team member), Liu, X. (Team member), Wen, X. (Team member), Zhang, J. (Team member), Wang, M. (Team member), Xu, M. (Team member), Cheng, K. (Team member), Zhang, X. (Team member), Song, J. (Team member), Guo, B. (Team member), Wang, Y. (Team member), Wang, J. (Team member), Wu, S. (Team member), Yang, J. (Team member), Fu, L. (Team member), Zhang, J. (Team member), Qiao, Y. (Team member), Chen, Y. (Team member), Li, T. (Team member), Zhan, T. (Team member), Wan, Y. (Team member), He, Z. (Team member), Cheng, Y. (Team member), Leng, J. (Team member), Qi, M. (Team member), Ho, J. (Team member), Sun, Y. (Team member), Zhang, N. (Team member), Soe, H. M. S. H. (Team member), Ling, C. (Team member), Zhou, H. (Team member), Huang, D. (Team member) & Gu, J. (Team member)
1/07/24 → 30/06/27
Project: Governmental Research Project
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Endosomal protein DENND10 promotes developmental competence of neurite extension
Li, A., Zhang, J., Ma, C., Qi, L., Hu, Q., Li, Q., Fang, Y., Song, J., Liu, Y. & Zhang, Y., 16 May 2025, In: iScience. 28, 5, 112385.Research output: Contribution to journal › Article › peer-review
Open Access -
Analysis of PD-1/PD-L1 variations in lung cancer and association with immunotherapeutic efficacy and prognosis: A nonrandomized controlled trial
Ma, J., Song, J. R., Han, L. N., Zhou, W., Meng, L. F., Li, J. H. & Bai, X. M., 1 Jan 2024, In: Clinics. 79, 100395.Research output: Contribution to journal › Article › peer-review
Open Access -
Endosomal protein DENND10/FAM45A integrates extracellular vesicle release with cancer cell migration.
Sun, S., Li, Q., Liu, G., Huang, X., Li, A., Guo, H., Qi, L., Zhang, J., Song, J., Su, X. & Zhang, Y., Jul 2024, In: BMC Biology. 22, 1Research output: Contribution to journal › Article › peer-review
File3 Citations (Scopus)364 Downloads (Pure) -
Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice
Song, J., Zhang, Y., Frieler, R. A., Andren, A., Wood, S., Tyrrell, D. J., Sajjakulnukit, P., Deng, J. C., Lyssiotis, C. A., Mortensen, R. M., Salmon, M. & Goldstein, D. R., 10 Feb 2024, In: Journal of Clinical Investigation. 134, 3, e173034.Research output: Contribution to journal › Article › peer-review
Open Access52 Citations (Scopus) -
Publisher Correction: Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice(Nature Aging, 10.1038/s43587-023-00515-w)
Tyrrell, D. J., Wragg, K. M., Chen, J., Wang, H., Song, J., Blin, M. G., Bolding, C., Vardaman, D., Giles, K., Tidwell, H., Ali, M. A., Janappareddi, A., Wood, S. C. & Goldstein, D. R., Aug 2024, In: Nature Aging. 4, 8, p. 1166 1 p.Research output: Contribution to journal › Comment/debate
1 Citation (Scopus)
Activities
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Nonconventional cell death modalities–mitoxyperilysis and more
Song, J. (Member of programme committee)
13 Dec 2025Activity: Participating in or organising an event › Participating in an event e.g. a conference, workshop, …
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Preparing Your PhD Students for Thesis Submission and Viva Examination
Song, J. (Participant)
12 Dec 2025Activity: Participating in or organising an event › Participating in an event e.g. a conference, workshop, …
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Protein Lipid Modification: Natural and Non-Natural Applications
Song, J. (Participant)
10 Dec 2025Activity: Participating in or organising an event › Participating in an event e.g. a conference, workshop, …
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2026 NSFC Grant Application - Experience Sharing Workshop (External Speaker) – Life and Health Sciences
Song, J. (Participant)
10 Dec 2025Activity: Participating in or organising an event › Participating in an event e.g. a conference, workshop, …
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Chromatin Remodeling Checkpoints of β-cell Dysfunction in Type 2 Diabetes
Song, J. (Organiser)
5 Dec 2025Activity: Participating in or organising an event › Organising an event e.g. a conference, workshop, …