Projects per year
Personal profile
Personal profile
Dr. Song joined the Academy of Pharmacy, Xi’an Jiaotong-Liverpool University as an Assistant Professor in Jan 2024. Dr. Song received her Ph.D degree in Cell and Developmental Biology from the University of Michigan, Ann Arbor. Afterwards, she did her postdoctoral training in Dr. Daniel Goldsteins lab. She gained her expertise in aging, immunity, adipose tissue and cardiovascular diseases (CVDs) including hypertension, myocardial infarction and atherosclerosis. Dr. Song and her laboratory is interested in how aging impacts immunity and immune cell metabolism in disease models including CVDs, cancer and obesity. Currently, their work focuses on areas of immunity, inflammation, aging, metabolism, adipose tissue and autophagy.
Research interests
1. Obesity promotes cancer development and progression during aging.
2. How itaconate suppresses inflammation to improve cardiovascular diseases.
3. Activate immunity through autophagy to fight against cancer with age.
4. Immune cell metabolism reprogramming in disease models like cardiovascular diseases and cancer.
Experience
Postdoctoral Research Fellow, University of Michigan, Ann Arbor USA 2018-2023
Research Assistant, Eastern Hepatobiliary Surgery Hospital, Shanghai China 2009-2012
Awards and honours
2nd Prize of Shanghai Science and Technology Award, The Shanghai Municipal Peoples Government
The Ming K.Jeang scholarship Award, Society of Chinese Bioscientists in America
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Ph.D, Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA 2012-2018
MMed, Oncology, Second Military Medical University, Shanghai China 2006-2009
Person Types
- Staff
Fingerprint
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Collaborations and top research areas from the last five years
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Projects
- 2 Active
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Mechanistic investigation about the anti-inflammatory role of itaconate in atherosclerosis
1/07/24 → 30/06/27
Project: Internal Research Project
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Jiangsu Province Higher Education Key Laboratory of Cell Therapy Nanoformulation (Construction)
Ruan, G., Lee, M. H., Wu, Q., Lu, T., Xu, P., Loo, S., Sun, Y., Kam, A., Liu, X., Wen, X., Zhang, J., Wang, M., Xu, M., Cheng, K., Zhang, X., Song, J., Guo, B., Wang, Y., Wang, J., Wu, S., Yang, J., Fu, L., Zhang, J., Qiao, Y., Chen, Y., Li, T., Huang, D., Gu, J., Zhan, T., Wan, Y., He, Z., Cheng, Y., Leng, J., Qi, M., Ho, J., Sun, Y., Zhang, N., Soe, H. M. S. H., Ling, C. & Zhou, H.
1/07/24 → 30/06/27
Project: Governmental Research Project
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Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice
Song, J., Zhang, Y., Frieler, R. A., Andren, A., Wood, S., Tyrrell, D. J., Sajjakulnukit, P., Deng, J. C., Lyssiotis, C. A., Mortensen, R. M., Salmon, M. & Goldstein, D. R., 10 Feb 2024, In: Journal of Clinical Investigation. 134, 3, e173034.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
Publisher Correction: Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice(Nature Aging, 10.1038/s43587-023-00515-w)
Tyrrell, D. J., Wragg, K. M., Chen, J., Wang, H., Song, J., Blin, M. G., Bolding, C., Vardaman, D., Giles, K., Tidwell, H., Ali, M. A., Janappareddi, A., Wood, S. C. & Goldstein, D. R., Aug 2024, In: Nature Aging. 4, 8, p. 1166 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Age-associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis
Song, J., Farris, D., Ariza, P., Moorjani, S., Varghese, M., Blin, M., Chen, J., Tyrrell, D., Zhang, M., Singer, K., Salmon, M. & Goldstein, D. R., Feb 2023, In: Aging Cell. 22, 2, e13783.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice
Tyrrell, D. J., Wragg, K. M., Chen, J., Wang, H., Song, J., Blin, M. G., Bolding, C., Vardaman, D., Giles, K., Tidwell, H., Ali, M. A., Janappareddi, A., Wood, S. C. & Goldstein, D. R., Dec 2023, In: Nature Aging. 3, 12, p. 1576-1590 15 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Aconitate decarboxylase 1 regulates glucose homeostasis and obesity in mice
Frieler, R. A., Vigil, T. M., Song, J., Leung, C., Goldstein, D. R., Lumeng, C. N. & Mortensen, R. M., Sept 2022, In: Obesity. 30, 9, p. 1818-1830 13 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus)