Ghulam Md Ashraf

Associate Professor

Calculated based on number of publications stored in Pure and citations from Scopus
20072024

Research activity per year

Personal profile

Personal profile

Dr. Ashraf has an educational training in biochemistry and research expertise in neuroscience. He earned his PhD degree in Biochemistry from Aligarh Muslim University in 2010. During his doctoral work, he carried out fundamental research on purification, characterization and sequencing of galectin-1 from mammalian heart. He has 14 years of combined teaching, research, and innovation experience in biological, health, and medical sciences. During his academic career, he has focused on teaching concise course material, conducting productive research leading to publications, and contributing to a range of studies, curriculum planning, and innovation strategies. 

Dr. Ashraf has also been involved extensively in editorial roles with internationally reputed scientific journals like the Journal of Advanced Research (Associate Editor), Scientific Reports (Senior EBM), PLoS One (Academic Editor), Current Neuropharmacology (Section Editor), and Current Alzheimer Research (Section Editor). He has the credit of 641 Web of Science verified editor records and 675 Web of Science verified reviewer records. He has been involved as a guest editor of 21 special issues in reputed international journals and have participated in 33 scientific meetings around the world. He is professionally associated with the Royal Society of Medicine (Fellow), Royal Society of Biology (Member), American Society for Biochemistry and Molecular Biology (Member) and Canadian Association of Neuroscience (Member). 

Research interests

Dr. Ashraf’s primary fields of research is neuropharmacology, currently focusing on investigating the molecular and behavioral mechanisms of novel therapeutic combinations in multiple sclerosis. His lab also investigates the molecular and behavioral mechanism of effects of anti-diabetic drugs in psychotic and dementia conditions. He has published 424 research manuscripts (citations: 14566, H-index: 61, i10 index: 241) and been involved in 25 research grants. He has also supervised 3 PhD, 2 Masters, and 7 Bachelor students in their thesis-based research projects.

RESEARCH TRACK 1: Multiple sclerosis (MS) is a neurodegenerative disorder prevalent in young adults, and characterized by symptoms like muscle weakness in the arms and legs, trouble with coordination, fatigue, loss of feeling, speech problems, tremor, dizziness etc. Unlike other neurodegenerative disorders, the cognitive impairment and related symptoms in the patients of MS can be effectively attenuated with a well-planned diagnostic and therapeutic regimen. Ashraf's lab screens and identifies new prophylactic and therapeutic agents, investigates their effects in the animal model of MS, and explores the associated molecular and behavioral mechanistic alterations.

References:

https://pubmed.ncbi.nlm.nih.gov/38890237/

https://pubmed.ncbi.nlm.nih.gov/36688131/

https://pubmed.ncbi.nlm.nih.gov/35323389/

RESEARCH TRACK 2: When a patient with psychotic conditions like Schizophrenia or bipolar disorder reaches a clinic, the immediate medication prescribed by the clinician is an antipsychotic drug. While the antipsychotic drugs effectively normalize patients’ behavior, they quite often trigger the appetite center and the patients start to gain weight. When the antipsychotic drug-induced weight gain (ADWG) gets chronic, the only option left for the clinicians is start a medication to counter the growing weight. For many years, Metformin (an antidiabetic drug) has been a standard prescription for weight loss regimen. However, its long-term usage has been associated with severe gastrointestinal tract disorders, forcing the clinicians to prescribe insulin injections which comes with considerable side effects as well. Ashraf’s lab screens new anti-diabetic drugs, investigates their effect in ADWG in animal models, and explores the associated molecular and behavioral mechanistic alterations.

References:

https://pubmed.ncbi.nlm.nih.gov/33183202/

https://pubmed.ncbi.nlm.nih.gov/33953666/

Experience

2024-PRESENT: ASSOCIATE PROFESSOR, Department of Biological Sciences, School of Science, Xi’an Jiaotong-Liverpool University, Suzhou, Jiangsu, China. 

2022-2024: ASSOCIATE PROFESSOR, Department of Medical Laboratory Sciences, College of Health Sciences, University of Sharjah, United Arab Emirates. 

2017-2022: ASSOCIATE PROFESSOR, King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, Saudi Arabia 

2012-2017: ASSISTANT PROFESSOR, King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, Saudi Arabia 

2010-2012: LECTURER, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow, India. 

Teaching

2024-2025: BIO201 (Genome Expression and Maintenance)

2010-2024: Postgraduate: Advanced Clinical Chemistry, Enzymology, Enzyme Technology, Advanced Laboratory Techniques, Research Methods; Undergraduate: Biology, Biochemistry, Human Anatomy and Physiology, Intellectual Property Rights, Introduction to Research, Molecular Biology, Recombinant DNA Technology, Structural Biology

Awards and honours

  • Listed in Top 2% Scientists Worldwide, announced by Plos-Elsevier-Stanford University (2021-Present).
  • AD Scientific Index Biochemistry best scientist (rank 1) in UAE (2023-2024).
  • Expertscape World Expert in Alzheimer’s disease (Ranked 1st in UAE and Saudi Arabia, 10th in Asia, and 35th Worldwide) (2021-2024).
  • Expertscape World Expert in Neurodegenerative Diseases (Ranked 1st in UAE and Saudi Arabia, 12th in Asia, and 59th Worldwide) (2021-2024).
  • Outstanding Author Award by the journal Neural Regeneration Research (2021)
  • Approved as a subject of biographical record in Marquis Who's Who in the World (2020).
  • Elected as Fellow of the Royal Society of Medicine (FRSM, No: 00723087) (2020).
  • Elected as Member of American Society for Biochemistry and Molecular Biology (2020).
  • Elected as Member of the Royal Society of Biology (MRSB, No: P0139900) (2020).
  • Web of Science Top reviewers award in Biology and Biochemistry award (2019).
  • Web of Science Top reviewers award in Cross-Field award (2019).

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy
  • SDG 11 - Sustainable Cities and Communities
  • SDG 12 - Responsible Consumption and Production
  • SDG 14 - Life Below Water

Related documents

Education/Academic qualification

PhD, Biochemistry, Aligarh Muslim University

20062011

Award Date: 3 Feb 2010

External positions

VISITING SCIENTIST, Manipal Academy of Higher Education, Dubai, UAE.

2024 → …

RESEARCH FELLOW, INTI International University, Malaysia.

2023 → …

VISITING SCIENTIST, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, China.

2020 → …

Keywords

  • Q Science (General)
  • Neuroscience
  • Neurodegenerative Diseases
  • Multiple Sclerosis
  • Alzhiemer's Disease

Person Types

  • Staff

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