The digital economy promotes the increase and upgrade of industries, and Suzhou has been encouraging the development of the digital industry. Previous studies identified factors that contribute to the success of digital entrepreneurship. However, a successful result in the complex reality needs combinations of factors, and these factor combinations constitute success paths. This project explores the paths leading to the high performance of digital entrepreneurship in Suzhou by using the method of fuzzy-set qualitative comparative analysis (fs-QCA). Findings are meaningful to individuals who want successful digital entrepreneurship and essential to the government to develop the digital industry.