Mesenchymal stem cell-derived extracellular vesicles attenuate periductal fibrosis by inhibiting Th17 differentiation in human liver multilineage organoids and Mdr2 -/- mice.

Wenyi  Chen; Xinyi Chen; Feiqiong  Gao; Qigu  Yao; Sheng  Cheng; Qiaoling  Pan; Jiong  Yu; Jinfeng  Yang; Guanghua  Ma; Jintao  Gong; Qian  Li; Yunhua  Chen; Lee Wei Lim; Ilia  Stambler; Georgina M.  Ellison-Hughes; Brun  Ulfhake; Hongcui  Cao; Robert Chunhua  Zhao

Mesenchymal stem cell-derived extracellular vesicles attenuate periductal fibrosis by inhibiting Th17 differentiation in human liver multilineage organoids and Mdr2 -/- mice.

Wenyi Chen, Xinyi Chen, Feiqiong Gao, Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Jinfeng Yang, Guanghua Ma, Jintao Gong, Qian Li, Yunhua Chen, Lee Wei Lim, Ilia Stambler, Georgina M. Ellison-Hughes, Brun Ulfhake, Hongcui Cao, Robert Chunhua Zhao

Department of Biosciences and Bioinformatics

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Journal of Nanobiotechnology
Publication status	Published - Aug 2025

Cite this

Chen, W., Chen, X., Gao, F., Yao, Q., Cheng, S., Pan, Q., Yu, J., Yang, J., Ma, G., Gong, J., Li, Q., Chen, Y., Lim, L. W., Stambler, I., Ellison-Hughes, G. M., Ulfhake, B., Cao, H., & Zhao, R. C. (2025). Mesenchymal stem cell-derived extracellular vesicles attenuate periductal fibrosis by inhibiting Th17 differentiation in human liver multilineage organoids and Mdr2 -/- mice. Journal of Nanobiotechnology.

@article{f941604e49fd420d89edfb2ec1fd0999,

title = "Mesenchymal stem cell-derived extracellular vesicles attenuate periductal fibrosis by inhibiting Th17 differentiation in human liver multilineage organoids and Mdr2 -/- mice.",

author = "Wenyi Chen and Xinyi Chen and Feiqiong Gao and Qigu Yao and Sheng Cheng and Qiaoling Pan and Jiong Yu and Jinfeng Yang and Guanghua Ma and Jintao Gong and Qian Li and Yunhua Chen and Lim, {Lee Wei} and Ilia Stambler and Ellison-Hughes, {Georgina M.} and Brun Ulfhake and Hongcui Cao and Zhao, {Robert Chunhua}",

year = "2025",

month = aug,

language = "English",

journal = "Journal of Nanobiotechnology",

issn = "1477-3155",

}

Chen, W, Chen, X, Gao, F, Yao, Q, Cheng, S, Pan, Q, Yu, J, Yang, J, Ma, G, Gong, J, Li, Q, Chen, Y, Lim, LW, Stambler, I, Ellison-Hughes, GM, Ulfhake, B, Cao, H & Zhao, RC 2025, 'Mesenchymal stem cell-derived extracellular vesicles attenuate periductal fibrosis by inhibiting Th17 differentiation in human liver multilineage organoids and Mdr2 -/- mice.', Journal of Nanobiotechnology.

TY - JOUR

T1 - Mesenchymal stem cell-derived extracellular vesicles attenuate periductal fibrosis by inhibiting Th17 differentiation in human liver multilineage organoids and Mdr2 -/- mice.

AU - Chen, Wenyi

AU - Chen, Xinyi

AU - Gao, Feiqiong

AU - Yao, Qigu

AU - Cheng, Sheng

AU - Pan, Qiaoling

AU - Yu, Jiong

AU - Yang, Jinfeng

AU - Ma, Guanghua

AU - Gong, Jintao

AU - Li, Qian

AU - Chen, Yunhua

AU - Lim, Lee Wei

AU - Stambler, Ilia

AU - Ellison-Hughes, Georgina M.

AU - Ulfhake, Brun

AU - Cao, Hongcui

AU - Zhao, Robert Chunhua

PY - 2025/8

Y1 - 2025/8

M3 - Article

SN - 1477-3155

JO - Journal of Nanobiotechnology

JF - Journal of Nanobiotechnology

ER -