How can we deal with Flavobacterium psychrophilum, a problematic fish pathogen in salmonids

Activity: Talk or presentationInvited talk

Description

Flavobacterium psychrophilum is the causative agent of bacterial cold-water disease (BCWD) in salmonids worldwide, resulting in substantial economic losses in aquaculture. Prevention of this disease mainly relies on antibiotics and no licensed commercial vaccines are currently available. It has been verified that the type IX secretion system (T9SS) is involved in the pathogenesis of F. psychrophilum but the mechanism is not well understood. Genetic manipulation of F. psychrophilum strains has been problematic, hampering our ability to better understand host-pathogen interactions as a step toward improved control measures. In this talk, I will present our recent breakthrough on the development of genetic manipulation tools in F. psychrophilum, discuss the roles of T9SS and other possible virulence factors, and initiate discussions on developing feasible strategies, such as using live attenuated vaccines, to prevent BCWD.
Period6 Sept 2024
Held atHeilongjiang River Fisheries Research Institute of CASF
Degree of RecognitionNational